Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 4/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 3/20 | 0.33 |
| ▸ | CYCS | P99999 | 2/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192147 | 0.96 | TERT (0.35) | TERTABCG2TOP1CYCS | |
| SCHEMBL14192146 | 0.88 | TYMS (0.32) | — | |
| SCHEMBL14192148 | 0.87 | TERT (0.32) | TERT | |
| SCHEMBL272097 | 0.86 | TERT (0.44) | TERTABCG2TOP1CYCSENPP2 | |
| SCHEMBL30979189 | 0.84 | TERT (0.43) | TERTABCG2TOP1CYCSENPP2 | |
| SCHEMBL29666226 | 0.84 | TERT (0.43) | TERTABCG2TOP1CYCSENPP2 | |
| Magnesium SCHEMBL31249469 | 0.84 | TERT (0.43) | TERTABCG2TOP1CYCSENPP2 | |
| SCHEMBL8675997 | 0.81 | TERT (0.37) | TERTABCG2TOP1CYCSENPP2 | |
| SCHEMBL14192145 | 0.79 | TERT (0.35) | TERTABCG2TOP1CYCS | |
| SCHEMBL14285073 | 0.70 | TERT (0.34) | TERTTOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375215-B2 | tetrakis(hydroxyphenyl)chlorin, bacteriochlorin or isobacteriochlorin, derivatised at one or more of the hydroxy groups by addition reaction with a diisocyanate, diisothiocyanate or isocyanate; photodynamic therapy of cancerous and other diseased tissues | BIOSCIENCE TECHNOLOGY INVESTMENT HOLDINGS LIMITED (MY) | 2008-05-20 | — | — | US | disclosed |
| US-7276494-B2 | Photosensitisers | PHOTOPHARMICA LIMITED (GB) | 2007-10-02 | — | — | US | disclosed |
| US-5847034-A | Porphyrin-containing silicones having increased thermal stability | WACKER-CHEMIE GMBH (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0748838-A1 | Porphyrin-containing silicones with improved temperature resistance | Wacker-Chemie GmbH (DE) | 1996-12-18 | — | — | EP | disclosed |