Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.43 |
| ▸ | TOP1 | P11387 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | CYCS | P99999 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272097 | 0.98 | TERT (0.44) | TERTTOP1ABCG2CYCSENPP2 | |
| SCHEMBL29666226 | 0.95 | TERT (0.43) | TERTTOP1ABCG2CYCSENPP2 | |
| SCHEMBL30979189 | 0.95 | TERT (0.43) | TERTTOP1ABCG2CYCSENPP2 | |
| SCHEMBL17688993 | 0.84 | TERT (0.37) | TERTTOP1ABCG2CYCS | |
| SCHEMBL8676003 | 0.84 | TERT (0.37) | TERTTOP1ABCG2CYCSENPP2 | |
| SCHEMBL8675997 | 0.84 | TERT (0.37) | TERTTOP1ABCG2CYCSENPP2 | |
| SCHEMBL768992 | 0.81 | TERT (0.57) | TERTTOP1ABCG2CYCSENPP2 | |
| SCHEMBL15943764 | 0.81 | TERT (0.57) | TERTTOP1ABCG2CYCSENPP2 | |
| SCHEMBL14192147 | 0.81 | TERT (0.35) | TERTTOP1ABCG2CYCS | |
| SCHEMBL14192145 | 0.81 | TERT (0.35) | TERTTOP1ABCG2CYCS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125660-A1 | MODIFIED ARCHAEAL FAMILY B POLYMERASES | SINGULAR GENOMICS SYSTEMS INC (US) | 2026-05-07 | — | — | US | disclosed |
| US-20240401009-A1 | MODIFIED THERMOCCOCUS POLYMERASES | FIRST-CITIZENS BANK & TRUST COMPANY | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125660-A1 | MODIFIED ARCHAEAL FAMILY B POLYMERASES | DNMT3A, POLB, POLM | TERT 369/4885TOP1 379/4885ABCG2 2193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.