SCHEMBL4613181

SCHEMBL4613181

C/C=C/C(=O)OC(O)CCC

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.32
ATM Q13315 1/20 0.32
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32
SLC6A3 Q01959 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GSTP1 P09211 1/20 0.32
CYP3A4 P08684 2/20 0.31
TSHR P16473 2/20 0.31
NFKB1 P19838 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
TAS1R3 Q7RTX0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4613185 1.00 HCAR2 (0.32) HCAR2ATMCHRM1AKR1A1CHRM3
SCHEMBL8676086 0.90 HCAR2 (0.40) HCAR2ATMCHRM1AKR1A1CHRM3
SCHEMBL8676089 0.90 HCAR2 (0.40) HCAR2ATMCHRM1AKR1A1CHRM3
SCHEMBL9398163 0.87 ACHE (0.34) ACHEBACE1
SCHEMBL11455121 0.87 GPR84 (0.40) HCAR2ATMNFKB1
SCHEMBL9398153 0.87 ACHE (0.34) ACHEBACE1
SCHEMBL182377 0.83 TSHR (0.39) HCAR2ATMGSTP1TSHR
SCHEMBL11269481 0.83 CHRM1 (0.34) ATMCHRM1AKR1A1CHRM3HTR2A
SCHEMBL182379 0.83 TSHR (0.39) HCAR2ATMGSTP1TSHR
SCHEMBL10396797 0.82 HCAR2 (0.53) HCAR2ATMCHRM1AKR1A1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1751201-B1 OLIGOMER SUITABLE FOR COATING COMPOSITIONS FOR WOOD SUBSTRATES PPG IND OHIO INC (US) 2008-10-29 EP disclosed
US-7417100-B2 Transparent fluorine-containing copolymer CENTRAL GLASS COMPANY, LIMITED (JP) 2008-08-26 US disclosed
US-7387843-B2 Alkyd-based free radical wood coating compositions PPG INDUSTRIES OHIO, INC. (US) 2008-06-17 US disclosed
EP-1751201-A1 OLIGOMER SUITABLE FOR COATING COMPOSITIONS FOR WOOD SUBSTRATES PPG Industries Ohio, Inc. (US) 2007-02-14 EP disclosed
US-7151122-B2 by actinic and/or ionizing radiation; coating of polysiloxanes or oligomers having pendant acryloyloxyalkylcarbamate or epoxyalkylcarbamate groups; such as polysiloxanes where a silicon hydride is transformed with trimethylolpropane monoallyl ether and then reacted with 2-methacryloyloxyethyl isocyanate PGG INDUSTRIES OHIO, INC. (US) 2006-12-19 US disclosed
WO-2006083338-A1 FUNCTIONALIZED THERMOSETTING RESIN SYSTEMS REICHHOLD, INC. (US) 2006-08-10 WO disclosed
US-20060173142-A1 Functionalized thermosetting resin systems REICHHOLD, INC. 2006-08-03 US disclosed
US-7060771-B2 Transparent fluorine-containing copolymer CENTRAL GLASS COMPANY, LIMITED (JP) 2006-06-13 US disclosed
US-20060063902-A1 Transparent fluorine-containing copolymer CENTRAL GLASS CO., LTD. (JP) 2006-03-23 US disclosed
US-7001667-B2 Alkyd-based free radical wood coating compositions PPG INDUSTRIES OHIO, INC. (US) 2006-02-21 US disclosed
US-20040013895-A1 Alkyd-based free radical wood coating compositions PPG INDUSTRIES OHIO, INC. 2004-01-22 US disclosed
US-20030236369-A1 Transparent fluorine-containing copolymer CENTRAL GLASS COMPANY, LIMITED (JP) 2003-12-25 US disclosed
US-6403744-B1 FLUORINE-CONTAINING COPOLYMER COMPRISING FIRST REPEATING UNIT DERIVED FROM OCTAFLUOROCYCLOPENTENE, SECOND REPEATING UNIT DERIVED FROM VINYL ETHERS, ALLYL ETHERS, PERFLUOROALKYL VINYL ETHERS AND/OR VINYL ESTERS CENTRAL GLASS COMPANY, LIMITED (JP) 2002-06-11 US disclosed
US-5880234-A POLYMER PREPARED BY COPOLYMERIZING MIXTURE OF HEXAFLUOROISOBUTYLENE OR HEXAFLUOROACETONE, FATTY ACID VINYL ESTER, MONOMER HAVING DOUBLE BOND AND CROSSLINKABLE FUNCTIONAL GROUP, ADDITIONAL DIFFERENT MONOMER CENTRAL GLASS COMPANY, LIMITED (JP) 1999-03-09 US disclosed
US-5399644-A Sulfur dioxide for vapor phase elimination of styrene and acrylonitrile popcorn polymer in bulk san production GENERAL ELECTRIC COMPANY (US) 1995-03-21 US disclosed
US-5272231-A Nitric oxide for vapor phase elimination of styrene and acrylonitrile popcorn polymer in bulk SAN production GENERAL ELECTRIC COMPANY (US) 1993-12-21 US disclosed
US-5256731-A Fluoropolymer or copolymers; protective coatings HOECHST AG (DE) 1993-10-26 US disclosed
US-4591518-A UNGELLED URETHANE MODIFIED RESIN CONTAINING PENDANT UNSATURATED GROUPS ATTACHED THROUGH URETHANE LINKAGES PPG INDUSTRIES, INC. (US) 1986-05-27 US disclosed
EP-0175097-A2 Acrylic functional urethane alkyd resin coating compositions PPG INDUSTRIES, INC. (US) 1986-03-26 EP disclosed
US-3960824-A Mercaptan initiated polymerization process carried out in the presence of oxygen CELANESE COATINGS & SPECIALTIES COMPANY (US) 1976-06-01 US disclosed