SCHEMBL8676261

SCHEMBL8676261

Oc1ccc(O)c2c1CC=CC2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.35
BCL2L1 Q07817 1/20 0.33
BAD Q92934 1/20 0.33
IDO1 P14902 1/20 0.33
FYN P06241 2/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
APP P05067 1/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
CA12 O43570 1/20 0.32
GMNN O75496 1/20 0.32
ALDH1A1 P00352 1/20 0.32
EGFR P00533 1/20 0.32
CA2 P00918 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
CA3 P07451 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3963857 0.80 PIM1 (0.35) PIM1BCL2L1BADIDO1FYN
SCHEMBL16772449 0.75 AURKA (0.33) MEN1KMT2AALDH1A1CYP3A4MAPT
SCHEMBL21092188 0.73 DRD2 (0.33) PIM1FYNALDH1A1EGFRCA2
SCHEMBL506663 0.73 BCL2L1 (0.50) BCL2L1BADFYNMEN1KMT2A
SCHEMBL6711459 0.72 BCL2L1 (0.42) PIM1BCL2L1BADIDO1FYN
SCHEMBL10638723 0.72
SCHEMBL16900577 0.69
SCHEMBL8662866 0.69
SCHEMBL14283955 0.67 MAOA (0.33) FYNMEN1GAAKMT2AMAOA
SCHEMBL10802712 0.67 BCL2L1 (0.50) PIM1BCL2L1BADIDO1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112409845-A Printing ink TCL集团股份有限公司 2021-02-26 CN claimed
CN-112409845-B Printing ink TCL科技集团股份有限公司 2022-03-01 CN disclosed
CN-112409845-A Printing ink TCL集团股份有限公司 2021-02-26 CN disclosed
EP-1515192-B1 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH CO LTD (JP) 2015-07-15 EP disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
CN-1249071-C Process for synthesis of optically active anthracyclines MENARINI RICERCHE SPA (IT) 2006-04-05 CN disclosed
CN-1474827-A Process for synthesis of optically active anthracyclines ÷�������о����ɷݹ�˾ 2004-02-11 CN disclosed
US-5723675-A DIELS-ALDER REACTION OF 1,4-NAPHTHOQUINONE, 1,4-BENZOQUINONE WITH 1,3-BUTADIENE AND DEHYDROGENATION WITH LEWIS ACID OR BRONSTED ACID AS OXIDATIVE CATALYST KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 1998-03-03 US disclosed
US-4975461-A Enzymes/oxidoreductases/inhibitors E. R. SQUIBB & SONS, INC. (US) 1990-12-04 US disclosed
EP-0109701-B1 DIFFUSION TRANSFER MATERIAL AGFA-GEVAERT N.V. (BE) 1986-12-17 EP disclosed
US-4477554-A SILVER HALIDE EMULSION CONTAINING QUINOID DYE-RELEASING COMPOUND AGFA-GEVAERT, N.V. (BE) 1984-10-16 US disclosed
EP-0109701-A1 Diffusion transfer material AGFA-GEVAERT N.V. (BE) 1984-05-30 EP disclosed
US-4267373-A HYDROXY- OR -OXY-SUBSTITUTED-6-ALKYL- OR DIALKYLAMINO-7-HYDROXY DERIVATIVES E. R. SQUIBB & SONS, INC. (US) 1981-05-12 US disclosed
US-4076843-A 5,6,7,8-Tetrahydronaphthalene hypotensive agents E. R. SQUIBB & SONS, INC. (US) 1978-02-28 US disclosed