Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.48 |
| ▸ | FNTB | P49356 | 5/20 | 0.48 |
| ▸ | CCKBR | P32239 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CCKAR | P32238 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | NOTCH1 | P46531 | 2/20 | 0.32 |
| ▸ | NOTCH3 | Q9UM47 | 2/20 | 0.32 |
| ▸ | NOTCH2 | Q04721 | 1/20 | 0.32 |
| ▸ | NOTCH4 | Q99466 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8671362 | 0.94 | FNTA (0.43) | FNTAFNTBCCKBRKCNH2CCKAR | |
| SCHEMBL8670222 | 0.91 | FNTA (0.42) | FNTAFNTBCCKBRKCNH2CCKAR | |
| SCHEMBL8668577 | 0.85 | FNTA (0.43) | FNTAFNTBCCKBRCCKARHDAC3 | |
| SCHEMBL8672877 | 0.84 | FNTA (0.37) | FNTAFNTBPGGT1BNOTCH1 | |
| SCHEMBL8801159 | 0.83 | FNTA (0.60) | FNTAFNTBCCKBRCCKARHDAC3 | |
| SCHEMBL8674098 | 0.82 | FNTA (0.46) | FNTAFNTBCCKBRCCKARHDAC3 | |
| SCHEMBL8669842 | 0.82 | CCKBR (0.38) | FNTAFNTBCCKBRKCNH2CCKAR | |
| SCHEMBL8672675 | 0.81 | FNTA (0.51) | FNTAFNTBCCKBRKCNH2CCKAR | |
| SCHEMBL8672718 | 0.81 | FNTA (0.46) | FNTAFNTBCCKBRKCNH2CCKAR | |
| SCHEMBL8800669 | 0.80 | FNTA (0.54) | FNTAFNTBCCKBRCCKARHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843941-A | Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1998-12-01 | — | — | US | disclosed |