Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.41 |
| ▸ | CCKBR | P32239 | 4/20 | 0.39 |
| ▸ | CCKAR | P32238 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674098 | 0.88 | FNTA (0.46) | FNTAFNTBSCN9ACCKBRCCKAR | |
| SCHEMBL8676294 | 0.85 | FNTA (0.48) | FNTAFNTBSCN9ACCKBRCCKAR | |
| SCHEMBL8668580 | 0.85 | SCN9A (0.42) | FNTAFNTBSCN9ACCKBRCCKAR | |
| SCHEMBL8672718 | 0.84 | FNTA (0.46) | FNTAFNTBSCN9ACCKBRCCKAR | |
| SCHEMBL8671362 | 0.83 | FNTA (0.43) | FNTAFNTBSCN9ACCKBRCCKAR | |
| SCHEMBL8801152 | 0.81 | FNTA (0.56) | FNTAFNTBSCN9ACCKBRCCKAR | |
| SCHEMBL8672675 | 0.77 | FNTA (0.51) | FNTAFNTBCCKBRCCKARHDAC3 | |
| SCHEMBL8670222 | 0.76 | FNTA (0.42) | FNTAFNTBCCKBRCCKARHDAC3 | |
| SCHEMBL8669186 | 0.73 | CCKBR (0.50) | SCN9ACCKBRCCKARHDAC3HDAC1 | |
| SCHEMBL8801922 | 0.71 | FNTA (0.58) | FNTAFNTBSCN9ACCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843941-A | Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1998-12-01 | — | — | US | disclosed |