Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8677142 | 0.88 | SRD5A2 (0.43) | SRD5A2NPSR1L3MBTL1CXCR2LMNA | |
| SCHEMBL8676367 | 0.86 | SRD5A2 (0.49) | SRD5A2FFAR1SRD5A1PTGS1PTGS2 | |
| SCHEMBL8678023 | 0.82 | L3MBTL1 (0.40) | SRD5A2NPSR1L3MBTL1CXCR2CYP2C9 | |
| SCHEMBL9371659 | 0.78 | SRD5A2 (0.56) | SRD5A2FFAR1SRD5A1PTGS1PTGS2 | |
| SCHEMBL8679798 | 0.78 | MAPT (0.43) | NPSR1L3MBTL1CXCR2LMNACYP2C9 | |
| SCHEMBL8679819 | 0.77 | PPARG (0.42) | NPSR1L3MBTL1CXCR2ALOX5CNR1 | |
| SCHEMBL8676564 | 0.76 | MAPT (0.42) | NPSR1L3MBTL1FFAR1CXCR2LMNA | |
| SCHEMBL8679538 | 0.76 | L3MBTL1 (0.42) | NPSR1L3MBTL1CXCR2CYP2C9 | |
| SCHEMBL9368473 | 0.76 | SRD5A2 (0.58) | SRD5A2FFAR1CHRM1PDE4APTGS1 | |
| SCHEMBL8676361 | 0.76 | SRD5A2 (0.59) | SRD5A2FFAR1SRD5A1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753641-A | SYNERGISTIC THERAPY COMPRISING FINASTERIDE AND TERAZOSIN DRUGS | MERCK & CO., INC. (US) | 1998-05-19 | — | — | US | disclosed |