SCHEMBL8676473

SCHEMBL8676473

N#Cc1ccc(CCCc2ccccc2C(=O)O)cc1F

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.44
FFAR4 Q5NUL3 1/20 0.44
FOLH1 Q04609 1/20 0.42
DAO P14920 1/20 0.42
TSHR P16473 1/20 0.40
SLC16A3 O15427 4/20 0.39
KCNJ1 P48048 1/20 0.39
KCNH2 Q12809 1/20 0.39
TAS2R14 Q9NYV8 2/20 0.39
BRS3 P32247 1/20 0.38
TRPV4 Q9HBA0 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.38
GPR52 Q9Y2T5 1/20 0.37
EP300 Q09472 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8678079 0.97 FFAR1 (0.44) FFAR1FFAR4FOLH1DAOTSHR
SCHEMBL8678443 0.96 FFAR1 (0.43) FFAR1FFAR4FOLH1DAOTSHR
SCHEMBL8678893 0.92 DAO (0.46) FFAR1FFAR4FOLH1DAOTSHR
SCHEMBL28984534 0.80 ALDH1A1 (0.42) TSHRSLC16A3EP300
SCHEMBL8676463 0.79 FOLH1 (0.49) FFAR1FFAR4FOLH1TSHRSLC16A3
SCHEMBL28984532 0.78 FOLH1 (0.40) FOLH1TSHRTAS2R14MRGPRX4
SCHEMBL1482485 0.75 MRGPRX4 (0.47) FFAR1FOLH1TRPV4MRGPRX4
SCHEMBL9514115 0.75 SLC16A3 (0.48) FFAR1FOLH1TSHRSLC16A3BRS3
SCHEMBL9514698 0.75 SLC16A3 (0.48) FFAR1FOLH1TSHRSLC16A3BRS3
SCHEMBL20162476 0.74 FOLH1 (0.61) FOLH1TSHRSLC16A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5720899-A Liquid crystalline compound, liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1998-02-24 US disclosed
US-5653911-A Liquid crystalline compound liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1997-08-05 US disclosed