SCHEMBL8678079

SCHEMBL8678079

N#Cc1ccc(CCCCc2ccccc2C(=O)O)cc1F

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44
FOLH1 Q04609 1/20 0.42
DAO P14920 1/20 0.42
SLC16A3 O15427 9/20 0.41
TSHR P16473 1/20 0.40
RARB P10826 2/20 0.39
RARA P10276 1/20 0.39
RARG P13631 1/20 0.39
KCNJ1 P48048 1/20 0.39
KCNH2 Q12809 1/20 0.39
TAS2R14 Q9NYV8 1/20 0.39
DHODH Q02127 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8678443 0.99 FFAR1 (0.43) FFAR1FFAR4FOLH1DAOSLC16A3
SCHEMBL8676473 0.97 FFAR1 (0.44) FFAR1FFAR4FOLH1DAOSLC16A3
SCHEMBL8678893 0.92 DAO (0.46) FFAR1FFAR4FOLH1DAOTSHR
SCHEMBL28984534 0.82 ALDH1A1 (0.42) SLC16A3TSHRRARBRARARARG
SCHEMBL28984532 0.78 FOLH1 (0.40) FOLH1TSHRTAS2R14
SCHEMBL9514115 0.78 SLC16A3 (0.48) FFAR1FOLH1SLC16A3TSHR
SCHEMBL9514698 0.78 SLC16A3 (0.48) FFAR1FOLH1SLC16A3TSHR
SCHEMBL8676463 0.76 FOLH1 (0.49) FFAR1FFAR4FOLH1SLC16A3TSHR
SCHEMBL1482485 0.75 MRGPRX4 (0.47) FFAR1FOLH1
SCHEMBL11710027 0.74 FOLH1 (0.61) FOLH1SLC16A3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5720899-A Liquid crystalline compound, liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1998-02-24 US disclosed
US-5653911-A Liquid crystalline compound liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1997-08-05 US disclosed