Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | KCNJ5 | P48544 | 4/20 | 0.53 |
| ▸ | KCNJ3 | P48549 | 4/20 | 0.53 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446184 | 0.81 | ALDH1A1 (0.50) | KCNJ5KCNJ3CTBP2PKMNPC1 | |
| Trifluoroacetic Acid SCHEMBL5658062 | 0.79 | PKM (0.51) | KCNJ5KCNJ3CTBP2PKMNPC1 | |
| SCHEMBL13061955 | 0.78 | CTBP2 (0.47) | KCNJ5KCNJ3CTBP2PKMNPC1 | |
| SCHEMBL14755023 | 0.78 | KCNJ5 (0.47) | KCNJ5KCNJ3CTBP2PKMNPC1 | |
| SCHEMBL6194349 | 0.77 | CTBP2 (0.58) | KCNJ5KCNJ3CTBP2PKMNPC1 | |
| SCHEMBL31365969 | 0.77 | CTBP2 (0.58) | KCNJ5KCNJ3CTBP2PKMNPC1 | |
| SCHEMBL27732144 | 0.77 | CES1 (0.55) | CES1KCNJ5KCNJ3HDAC1HDAC6 | |
| SCHEMBL28269575 | 0.77 | CES1 (0.55) | CES1NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL28757860 | 0.77 | CES1 (0.55) | CES1CTBP2NPC1SHBGALDH1A1 | |
| SCHEMBL6960850 | 0.75 | CTBP2 (0.56) | KCNJ5KCNJ3CTBP2PKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542411-B1 | TETRAHYDROTHIENOPYRIDINE DERIVATIVES, FURO AND PYRROLO ANALOGS THEREOF AND THEIR PREPARATION AND USES FOR INHIBITING BLOOD PLATELET AGGREGATION | SANKYO CO (JP) | 1998-08-12 | — | — | EP | disclosed |
| US-5436242-A | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof for inhibiting blood platelet aggregation | SANKYO COMPANY, LIMITED (JP) | 1995-07-25 | — | — | US | disclosed |
| US-5288726-A | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation | UBE INDUSTRIES LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0542411-A2 | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation | Sankyo Company Limited (JP) | 1993-05-19 | — | — | EP | disclosed |