Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29766842 | 0.79 | CYP1A2 (1.00) | CYP1A2TSHRADRA2AADRA1DADRA1A | |
| SCHEMBL8674200 | 0.79 | CYP1A2 (0.70) | CYP1A2TSHRTIPARPADRA2AROCK2 | |
| SCHEMBL8673343 | 0.79 | CYP1A2 (1.00) | CYP1A2TSHRADRA2AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL8671262 | 0.78 | CYP1A2 (0.97) | CYP1A2TSHRADRA2AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL8675065 | 0.76 | CYP1A2 (0.65) | CYP1A2TSHRADRA2AADRA1AALDH1A1 | |
| SCHEMBL8675357 | 0.76 | CYP1A2 (0.65) | CYP1A2TSHRTIPARPADRA2AADRA2B | |
| SCHEMBL8671092 | 0.73 | TIPARP (0.46) | TIPARPROCK2ALDH1A1MAPTHPGD | |
| SCHEMBL8672097 | 0.73 | TIPARP (0.46) | TIPARPADRA2AROCK2ADRA2BADRA2C | |
| SCHEMBL7305770 | 0.69 | HTR3E (0.40) | TIPARPMAPT | |
| SCHEMBL30101510 | 0.69 | TIPARP (0.59) | TIPARPROCK2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726197-A | ADRENORECEPTORS AND ADMINISTERING | SYNTEX (U.S.A.) INC. (US) | 1998-03-10 | — | — | US | disclosed |