Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.64 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.60 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.60 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.60 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675205 | 0.88 | PTGER1 (0.71) | ABCB1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8676630 | 0.88 | MTNR1A (0.55) | ABCB1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8321843 | 0.87 | PTGER1 (0.81) | ABCB1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8675521 | 0.86 | PTGER1 (0.67) | ABCB1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8677422 | 0.84 | PTGER1 (0.65) | ABCB1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL1388037 | 0.84 | RXRA (0.60) | ABCB1PTGER1TP53RXRAUSP2 | |
| SCHEMBL8674578 | 0.83 | PTGER4 (0.60) | ABCB1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8677356 | 0.82 | PTGER1 (0.59) | ABCB1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8323025 | 0.81 | PTGER4 (0.65) | ABCB1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL5333596 | 0.80 | USP2 (0.61) | ABCB1TP53USP2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |