Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8681372 | 0.90 | HDAC8 (0.32) | HDAC8HDAC6 | |
| SCHEMBL8679227 | 0.86 | — | — | |
| SCHEMBL8680548 | 0.83 | HPGD (0.38) | HDAC3HDAC1HDAC2 | |
| Butadiene SCHEMBL8677086 | 0.79 | HDAC8 (0.31) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| Butadiene SCHEMBL8678930 | 0.76 | ALDH1A1 (0.32) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| Butadiene SCHEMBL8678167 | 0.74 | — | — | |
| Butadiene SCHEMBL8677303 | 0.72 | — | — | |
| SCHEMBL8677580 | 0.71 | HDAC8 (0.30) | HDAC8HDAC6 | |
| Butadiene SCHEMBL8463299 | 0.71 | HDAC8 (0.30) | HDAC8HDAC6 | |
| Butadiene SCHEMBL8676911 | 0.67 | HPGD (0.37) | HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770538-A | Group 4 metal diene complexes and addition polymerization catalysts therefrom | THE DOW CHEMICAL COMPANY (US) | 1998-06-23 | — | — | US | disclosed |
| US-5539068-A | Group 4, metal-conjugated diene metallocyclopentene complexes, and addition polymerization catalysts therefrom | THE DOW CHEMICAL COMPANY (US) | 1996-07-23 | — | — | US | disclosed |
| US-5486632-A | Group 4 metal diene complexes and addition polymerization catalysts therefrom | THE DOW CHEMICAL COMPANY (US) | 1996-01-23 | — | — | US | disclosed |