Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8678565 | 0.90 | — | — | |
| Butadiene SCHEMBL8677086 | 0.89 | HDAC8 (0.31) | HDAC8HDAC6HSD11B1 | |
| SCHEMBL8681372 | 0.81 | HDAC8 (0.32) | HDAC8HDAC6 | |
| SCHEMBL8678698 | 0.80 | RAB9A (0.33) | — | |
| SCHEMBL8678558 | 0.79 | — | — | |
| SCHEMBL8679227 | 0.72 | — | — | |
| SCHEMBL8676598 | 0.71 | HSD11B1 (0.33) | HDAC8HDAC6HSD11B1 | |
| Butadiene SCHEMBL8677265 | 0.71 | HDAC8 (0.32) | HDAC8HDAC6 | |
| Butadiene SCHEMBL8678411 | 0.69 | RAB9A (0.34) | — | |
| SCHEMBL8678242 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770538-A | Group 4 metal diene complexes and addition polymerization catalysts therefrom | THE DOW CHEMICAL COMPANY (US) | 1998-06-23 | — | — | US | disclosed |
| US-5539068-A | Group 4, metal-conjugated diene metallocyclopentene complexes, and addition polymerization catalysts therefrom | THE DOW CHEMICAL COMPANY (US) | 1996-07-23 | — | — | US | disclosed |
| US-5486632-A | Group 4 metal diene complexes and addition polymerization catalysts therefrom | THE DOW CHEMICAL COMPANY (US) | 1996-01-23 | — | — | US | disclosed |