SCHEMBL8677463

SCHEMBL8677463

C=C(C(=C)[Si](C)(C)C)[Si](C)(C)C.O=CN[Ti]1(C2c3ccccc3-c3ccccc32)CC1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8677299 0.88 POLB (0.34) KMT2A
Butadiene SCHEMBL8678594 0.83 HDAC3 (0.31)
SCHEMBL8681257 0.83 MAPT (0.32)
SCHEMBL8678600 0.81 POLB (0.30)
SCHEMBL8681254 0.78 SIGMAR1 (0.30)
SCHEMBL8463485 0.72 TSHR (0.31) TSHRNPSR1KMT2A
SCHEMBL8679459 0.69
SCHEMBL8678392 0.68 POLB (0.33) KMT2A
Butadiene SCHEMBL8678330 0.66 GPR3 (0.31)
SCHEMBL8678560 0.65 SIGMAR1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5770538-A Group 4 metal diene complexes and addition polymerization catalysts therefrom THE DOW CHEMICAL COMPANY (US) 1998-06-23 US disclosed
US-5539068-A Group 4, metal-conjugated diene metallocyclopentene complexes, and addition polymerization catalysts therefrom THE DOW CHEMICAL COMPANY (US) 1996-07-23 US disclosed
US-5486632-A Group 4 metal diene complexes and addition polymerization catalysts therefrom THE DOW CHEMICAL COMPANY (US) 1996-01-23 US disclosed