SCHEMBL8677645

SCHEMBL8677645

C=C(C(=O)O)C(CC(C)C)(CC(C)C)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 1/20 0.33
GRM2 Q14416 1/20 0.33
GRM3 Q14832 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL811273 0.85 TET2 (0.36) TET2
SCHEMBL2139826 0.81 GRM2 (0.39) GRM2GRM3
SCHEMBL8678816 0.79 TET2 (0.31) TET2
SCHEMBL2722976 0.79
SCHEMBL16205189 0.77 TET2 (0.32) TET2
SCHEMBL6519386 0.76 CYP2C19 (0.36) TET2
SCHEMBL6515160 0.75 TET2 (0.35) TET2
SCHEMBL13269415 0.75 MMP8 (0.44)
SCHEMBL3896850 0.75 GRM2 (0.36) GRM2GRM3
SCHEMBL676152 0.75 TET2 (0.37) TET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3323841-B1 WHITE CARBON BLACK/POLY(ITACONATE-ISOPRENE-GLYCIDYL METHACRYLATE) BIO-BASED ELASTOMER COMPOSITE MATERIAL FREE OF SILANE COUPLING AGENT, AND PREPARATION METHOD THEREFOR UNIV BEIJING CHEM TECH (CN) 2020-04-22 EP claimed
EP-0697029-B1 AQUEOUS POLYMER DISPERSIONS AND THEIR USE IN THE PRODUCTION OF COATINGS WHICH ARE PERMEABLE TO WATER VAPOUR ROTTA GMBH (DE) 1998-08-26 EP disclosed