SCHEMBL16205189

SCHEMBL16205189

C=C(C(=O)O)C(CC(O)CO)(CC(O)CO)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 5/20 0.32
LMNA P02545 2/20 0.32
ALDH1A1 P00352 1/20 0.32
OR51E2 Q9H255 1/20 0.31
TET3 O43151 1/20 0.30
TET1 Q8NFU7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL811273 0.79 TET2 (0.36) TET2TET3TET1
SCHEMBL8677645 0.77 TET2 (0.33) TET2
SCHEMBL5178000 0.75 TET2 (0.33) TET2
SCHEMBL810647 0.71 TET2 (0.31) TET2
SCHEMBL2722976 0.69
Methacrylic Acid SCHEMBL27495155 0.69 TET2 (0.39) TET2LMNAALDH1A1OR51E2
Methacrylic Acid SCHEMBL28170966 0.69 TET2 (0.39) TET2LMNAALDH1A1OR51E2
Glycerin SCHEMBL8658278 0.69 LMNA (0.53) TET2LMNAALDH1A1OR51E2TET3
SCHEMBL676152 0.69 TET2 (0.37) TET2ALDH1A1
SCHEMBL14354020 0.68 ARG2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11839626-B2 Composition and kits for inhibition of pathogenic microbial infection and methods of using the same ROCHAL TECHNOLOGIES LLC (US) 2023-12-12 US disclosed
EP-3220741-B1 COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME ROCHAL IND LLC (US) 2021-02-24 EP disclosed
EP-3052140-B1 NON-SELF-ADHERENT COATING MATERIALS ROCHAL IND LLC (US) 2019-05-01 EP disclosed
US-20170360825-A1 Composition and Kits for Inhibition of Pathogenic Microbial Infection and Methods of Using the Same ROCHAL INDUSTRIES, LLC (US) 2017-12-21 US disclosed
EP-3220741-A1 COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME Rochal Industries, LLC (US) 2017-09-27 EP disclosed
EP-3052140-A1 NON-SELF-ADHERENT COATING MATERIALS Rochal Industries, LLC (US) 2016-08-10 EP disclosed
US-20160095876-A1 COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME CRG SERVICING LLC 2016-04-07 US disclosed
WO-2016054021-A1 COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME ROCHAL INDUSTRIES, LLC (US) 2016-04-07 WO disclosed
WO-2015050682-A1 NON-SELF-ADHERENT COATING MATERIALS ROCHAL INDUSTRIES, LLP (US) 2015-04-09 WO disclosed
US-8877882-B1 Non-self-adherent coating materials ROCHAL INDUSTRIES LLP (US) 2014-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160095876-A1 COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME CUTA, MMP8, MMP1 TET2 4764/4885LMNA 1246/4885ALDH1A1 4115/4885
US-20170360825-A1 Composition and Kits for Inhibition of Pathogenic Microbial Infection and Methods of Using the Same CUTA, MMP8, MMP1 TET2 4764/4885LMNA 1237/4885ALDH1A1 4110/4885
US-11839626-B2 Composition and kits for inhibition of pathogenic microbial infection and methods of using the same CUTA, MMP8, MMP1 TET2 4764/4885LMNA 1237/4885ALDH1A1 4110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.