SCHEMBL867788

SCHEMBL867788

CCC(C)OP(=O)(O)CC#N

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31191106 0.82 CTSA (0.36)
SCHEMBL4618579 0.81 TSHR (0.31)
SCHEMBL11525439 0.80 TSHR (0.34)
SCHEMBL11525772 0.79 TSHR (0.33)
SCHEMBL11524942 0.78
SCHEMBL776263 0.77 LAP3 (0.36) LAP3
SCHEMBL6487 0.76 LAP3 (0.32) LAP3
SCHEMBL1251447 0.75 PPARD (0.35) LAP3
SCHEMBL11745106 0.75 LAP3 (0.34) LAP3
SCHEMBL3090613 0.74 METAP1 (0.36) LAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115836065-A Methods of making JAK1 inhibitors 因赛特公司 2023-03-21 CN claimed
CN-114512716-A Gel electrolyte and preparation and application of precursor electrolyte thereof 中南大学 2022-05-17 CN claimed
US-8062816-B2 Phosphonate hole blocking layer photoconductors XEROX CORPORATION (US) 2011-11-22 US claimed
US-8053151-B2 Phosphonate containing photoconductors XEROX CORPORATION (US) 2011-11-08 US claimed
EP-2141545-A1 Phosphonate containing photoconductors Xerox Corporation (US) 2010-01-06 EP claimed
US-20090325091-A1 PHOSPHONATE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-31 US claimed
US-20090297967-A1 PHOSPHONATE HOLE BLOCKING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-03 US claimed
EP-2128709-A1 Phosphonate Hole Blocking Layer Photoconductors Xerox Corporation (US) 2009-12-02 EP claimed
EP-3694846-B1 1-BENZYL-2-IMINO-4-PHENYL-5-OXOIMIDAZOLIDINE DERIVATIVES AS HIV PROTEASE INHIBITORS GILEAD SCIENCES INC (US) 2024-05-08 EP disclosed
CN-115010754-A Preparation method of (1-cyanoethyl) diethyl phosphate 苏州昊帆生物股份有限公司 2022-09-06 CN disclosed
EP-3808743-B1 HIV REPLICATION INHIBITING PYRIMIDINES JANSSEN PHARMACEUTICA NV (BE) 2022-07-20 EP disclosed
US-11352329-B2 HIV protease inhibitors GILEAD SCIENCES, INC. (US) 2022-06-07 US disclosed
CN-114512716-A Gel electrolyte and preparation and application of precursor electrolyte thereof 中南大学 2022-05-17 CN disclosed
CN-111018771-B Method for synthesizing 3- (2-cyanovinyl) indole derivative 中国科学院大连化学物理研究所 2022-03-29 CN disclosed
WO-2004050068-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A BASIC RESPECTIVELY ACIDIC DRUG COMPOUND, A SURFACTANT AND A PHYSIOLOGICALLY TOLERABLE WATER-SOLUBLE ACID RESPECTIVELY BASE JANSSEN PHARMACEUTICA N.V. (BE) 2004-06-17 WO disclosed
EP-1419152-A1 HIV INHIBITING PYRIMIDINES DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 2004-05-19 EP disclosed
WO-2003016306-A1 HIV INHIBITING PYRIMIDINES DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 2003-02-27 WO disclosed
US-6284779-B1 NERVOUS SYSTEM DISORDERS SCHERING AKTIIENGESELLSCHAFT (DE) 2001-09-04 US disclosed
WO-2000046222-A1 HETEROAROMATIC COMPOUNDS WITH NEURONAL ACTIVITY SCHERING AKTIENGESELLSCHAFT (DE) 2000-08-10 WO disclosed
US-4151229-A Process for the manufacture of aminoalkyl-phosponic acid esters CIBA-GEIGY CORPORATION (US) 1979-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11352329-B2 HIV protease inhibitors PRSS1, SERPINB1, FURIN LAP3 265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.