Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.58 |
| ▸ | DRD2 | P14416 | 4/20 | 0.58 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4129639 | 0.82 | HTR1A (0.56) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL17197391 | 0.81 | HTR1A (0.79) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL8678015 | 0.81 | PTGER1 (0.55) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL8326278 | 0.79 | PTGER4 (0.68) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL8326275 | 0.79 | PTGER1 (0.63) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL5535502 | 0.78 | HTR1A (0.59) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL9057460 | 0.78 | HTR1A (0.79) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL330827 | 0.78 | MIF (0.42) | MGLL | |
| SCHEMBL29825231 | 0.78 | MIF (0.42) | MGLL | |
| SCHEMBL9277698 | 0.77 | HTR1A (0.71) | HTR1ADRD2PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |