SCHEMBL330827

SCHEMBL330827

O=C=NCCCc1ccccc1CCCN=C=O

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MIF P14174 4/20 0.42
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
NAAA Q02083 4/20 0.36
KEAP1 Q14145 4/20 0.36
NFE2L2 Q16236 4/20 0.36
TRPA1 O75762 1/20 0.32
CYP2E1 P05181 1/20 0.32
CYP2A6 P11509 1/20 0.32
HIF1A Q16665 1/20 0.32
CYP2A13 Q16696 1/20 0.32
EPAS1 Q99814 1/20 0.32
HTR3A P46098 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29825231 1.00 MIF (0.42) MIFGABRA1GABRB2NAAAKEAP1
SCHEMBL111622 0.94 MIF (0.44) MIFGABRA1GABRB2NAAAKEAP1
SCHEMBL30950301 0.94 MIF (0.44) MIFGABRA1GABRB2NAAAKEAP1
SCHEMBL5270497 0.87 MIF (0.40) MIFGABRA1GABRB2NAAAKEAP1
SCHEMBL29846915 0.86 MIF (0.39) MIFGABRA1GABRB2NAAAKEAP1
SCHEMBL111243 0.86 MIF (0.39) MIFGABRA1GABRB2NAAAKEAP1
SCHEMBL3476768 0.86 MIF (0.34) MIF
SCHEMBL28393828 0.86 GABRA1 (0.37) MIFGABRA1GABRB2NAAAKEAP1
SCHEMBL352781 0.85 NAAA (0.41) MIFGABRA1GABRB2NAAAKEAP1
SCHEMBL11431707 0.84 CYP1A2 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 570 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11267953-B2 Iso(thio)cyanate composition, and resin composition including same for optical member HOYA LENS THAILAND LTD. (TH) 2022-03-08 US claimed
US-20200123345-A1 ISO(THIO)CYANATE COMPOSITION, AND RESIN COMPOSITION INCLUDING SAME FOR OPTICAL MEMBER HOYA LENS THAILAND LTD. (TH) 2020-04-23 US claimed
US-10544283-B2 Iso(thio)cyanate composition, and resin composition including same for optical member HOYA LENS THAILAND LTD. (TH) 2020-01-28 US claimed
US-20180037722-A1 ISO(THIO)CYANATE COMPOSITION, AND RESIN COMPOSITION INCLUDING SAME FOR OPTICAL MEMBER HOYA LENS THAILAND LTD. (TH) 2018-02-08 US claimed
EP-3269749-A1 ISO(THIO)CYANATE COMPOSITION, AND RESIN COMPOSITION INCLUDING SAME FOR OPTICAL MEMBER Hoya Lens Thailand Ltd. (TH) 2018-01-17 EP claimed
EP-4748866-A1 AQUEOUS POLYURETHANE DISPERSIONS AND APPLICATIONS THEREOF Covestro Deutschland AG (DE) 2026-05-27 EP disclosed
US-12606692-B2 Spectacle lens HOYA LENS THAILAND LTD. (TH) 2026-04-21 US disclosed
US-12590232-B2 Multi-region foldable adhesive film and fabrication method therefor XINMEI FONTANA HOLDING (HONG KONG) LIMITED (CN) 2026-03-31 US disclosed
EP-3983466-B1 AQUEOUS POLYURETHANE DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2026-02-18 EP disclosed
EP-3778170-B1 METHOD FOR MANUFACTURING OPTICAL MEMBER HOYA LENS THAILAND LTD (TH) 2026-01-28 EP disclosed
US-12503575-B2 Fine hollow particles comprising melamine-based resin KAGOSHIMA UNIVERSITY (JP) 2025-12-23 US disclosed
EP-3786154-B1 PREPARATION METHOD FOR POLYTHIOL HAVING IMPROVED STORAGE STABILITY SK PUCORE CO LTD (KR) 2025-08-20 EP disclosed
EP-0528590-A1 Mercapto compound, its preparation process, and sulfur-containing urethane resins and lenses using the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-02-24 EP disclosed
EP-0506315-A2 Optical urethane resins and plastic lenses comprising the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-30 EP disclosed
EP-0505150-A1 Stabilizing method of isocyanate compounds and isocyanate compositions stabilized thereby MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-23 EP disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
US-4946923-A S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-08-07 US disclosed
EP-0378895-A1 A mercapto compound, a high refractive index resin and lens and a process for preparing them MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-07-25 EP disclosed
EP-0329388-A2 Plastic lenses having high-refractive index and process for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed
EP-0329386-A2 S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590232-B2 Multi-region foldable adhesive film and fabrication method therefor CDH1, SMCHD1, VCL MIF 537/4885GABRA1 524/4885GABRB2 1038/4885
US-12606692-B2 Spectacle lens POT1, TCOF1, CRY1 MIF 1569/4885GABRA1 711/4885GABRB2 1998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.