Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5988255 | 0.89 | GABRA1 (0.46) | SLC6A4SLC6A2SLC6A3ALDH1A1LMNA | |
| SCHEMBL29729780 | 0.83 | ALDH1A1 (0.57) | SLC6A4SLC6A2SLC6A3ALDH1A1TSHR | |
| SCHEMBL125255 | 0.83 | ALDH1A1 (0.57) | SLC6A4SLC6A2SLC6A3ALDH1A1TSHR | |
| SCHEMBL8677026 | 0.82 | TSHR (0.44) | ALDH1A1TSHRLMNAKDM4EMEN1 | |
| SCHEMBL3459705 | 0.80 | GABRA1 (0.44) | SLC6A4SLC6A2ALDH1A1LMNAPOLB | |
| SCHEMBL1129263 | 0.80 | CYP2D6 (0.41) | SLC6A4SLC6A2SLC6A3LMNACYP2D6 | |
| SCHEMBL28052525 | 0.80 | GABRA1 (0.40) | SLC6A4SLC6A2SLC6A3ALDH1A1TSHR | |
| SCHEMBL13692275 | 0.80 | GABRA1 (0.44) | SLC6A4SLC6A2ALDH1A1LMNAPOLB | |
| Alcohol SCHEMBL28875867 | 0.79 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3ALDH1A1TSHR | |
| SCHEMBL8567646 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TSHRLMNAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723398-A | CATALYST OF METAL CYCLOPENTADIENYL COMPLEX FOR POLYMERIZATION | THE DOW CHEMICAL COMPANY (US) | 1998-03-03 | — | — | US | disclosed |
| US-5494874-A | TITANIUM COMPLEXES WITH A COCATALYST AS POLYMERIZATION CATALYSTS | THE DOW CHEMICAL COMPANY (US) | 1996-02-27 | — | — | US | disclosed |
| US-5374696-A | Catalyzing the addition polymerization in presence of titanium metal complexes with cocatalysts | THE DOW CHEMICAL COMPANY (US) | 1994-12-20 | — | — | US | disclosed |