SCHEMBL8678239

SCHEMBL8678239

CCC(OC([NH])=O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.44
KMT2A Q03164 2/20 0.41
POLB P06746 2/20 0.41
MEN1 O00255 1/20 0.41
KLK7 P49862 1/20 0.41
PABPC1 P11940 1/20 0.40
APOBEC3A P31941 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ALDH1A1 P00352 3/20 0.40
ALKBH1 Q13686 1/20 0.39
MMP8 P22894 1/20 0.39
IGLV6-57 P01721 1/20 0.39
GAA P10253 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8678282 0.87 LMNA (0.45) LMNAKMT2APOLBMEN1KLK7
SCHEMBL983637 0.85 LMNA (0.47) LMNAKMT2APOLBMEN1KLK7
SCHEMBL6665775 0.85 LMNA (0.47) LMNAKMT2APOLBMEN1KLK7
SCHEMBL648756 0.85 LMNA (0.47) LMNAKMT2APOLBMEN1KLK7
SCHEMBL664962 0.83 PABPC1 (0.55) LMNAKMT2APOLBMEN1KLK7
SCHEMBL9608808 0.83 PABPC1 (0.55) LMNAKMT2APOLBMEN1KLK7
SCHEMBL2294116 0.83 PABPC1 (0.55) LMNAKMT2APOLBMEN1KLK7
SCHEMBL8465667 0.81 LMNA (0.45) LMNAKMT2APOLBMEN1KLK7
SCHEMBL2936559 0.81 KMT2A (0.44) LMNAKMT2APOLBMEN1KLK7
SCHEMBL8158169 0.81 KMT2A (0.44) LMNAKMT2APOLBMEN1KLK7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2497475-A1 Treatment of laminitis with platelet aggregation inhibitors Dussler, Sabine (DE) 2012-09-12 EP disclosed
EP-0542411-B1 TETRAHYDROTHIENOPYRIDINE DERIVATIVES, FURO AND PYRROLO ANALOGS THEREOF AND THEIR PREPARATION AND USES FOR INHIBITING BLOOD PLATELET AGGREGATION SANKYO CO (JP) 1998-08-12 EP disclosed
US-5691319-A ANTICARCINOGENIC AGENTS SANKYO COMPANY, LIMITED (JP) 1997-11-25 US disclosed
EP-0536936-B1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use SANKYO CO (JP) 1996-08-14 EP disclosed
US-5436242-A Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof for inhibiting blood platelet aggregation SANKYO COMPANY, LIMITED (JP) 1995-07-25 US disclosed
US-5288726-A Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation UBE INDUSTRIES LIMITED (JP) 1994-02-22 US disclosed
EP-0542411-A2 Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation Sankyo Company Limited (JP) 1993-05-19 EP disclosed
EP-0536936-A1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use Sankyo Company Limited (JP) 1993-04-14 EP disclosed