Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676665 | 0.93 | TDP1 (0.51) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL8675215 | 0.83 | TDP1 (0.48) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL8676387 | 0.82 | PTGER1 (0.62) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL8678347 | 0.79 | HTR1A (0.62) | TDP1KMT2ALMNAL3MBTL1PTGER1 | |
| SCHEMBL8326623 | 0.79 | PTGER1 (0.69) | KMT2APTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8678253 | 0.79 | CNR2 (0.48) | L3MBTL1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8675525 | 0.79 | PTGER1 (0.61) | TDP1KMT2ASLC6A2SLC6A3ESR1 | |
| SCHEMBL8698807 | 0.77 | TDP1 (0.64) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL8328747 | 0.77 | MAPT (0.54) | KMT2ALMNAL3MBTL1PTGER1PTGER4 | |
| SCHEMBL8698908 | 0.76 | TDP1 (0.62) | TDP1KMT2ASLC6A2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |