Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31441037 | 1.00 | PNMT (0.45) | PNMTNPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL15232909 | 0.87 | PNMT (0.41) | PNMTNPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL32662837 | 0.80 | PNMT (0.42) | PNMTNPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL2746886 | 0.79 | PNMT (0.39) | PNMTNPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL1033059 | 0.78 | TRPA1 (0.50) | PNMTNPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL30940563 | 0.78 | TRPA1 (0.50) | PNMTNPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL6847083 | 0.77 | PNMT (0.42) | PNMTNPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL739760 | 0.77 | PNMT (0.49) | PNMTNPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL1766127 | 0.77 | PNMT (0.49) | PNMTNPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL1612050 | 0.77 | PNMT (0.49) | PNMTNPC1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705578-A | Method for making and using a supported metallocene catalyst system | PHILLIPS PETROLEUM COMPANY (US) | 1998-01-06 | — | — | US | disclosed |