Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 5/20 | 0.44 |
| ▸ | MC3R | P41968 | 5/20 | 0.44 |
| ▸ | MC5R | P33032 | 4/20 | 0.44 |
| ▸ | AKT1 | P31749 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1231760 | 0.92 | HDAC3 (0.53) | HDAC3HDAC1HDAC2NCOR2LIMK2 | |
| SCHEMBL8525848 | 0.89 | HDAC3 (0.56) | HDAC3HDAC1HDAC2NCOR2CTSL | |
| SCHEMBL30940776 | 0.88 | MC5R (0.46) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL1848202 | 0.87 | HDAC1 (0.52) | HDAC3HDAC1HDAC2NCOR2CTSL | |
| SCHEMBL8021840 | 0.87 | HDAC3 (0.55) | HDAC3HDAC1HDAC2NCOR2CTSL | |
| SCHEMBL8331481 | 0.86 | SSTR4 (0.42) | HDAC3HDAC1HDAC2NCOR2MC4R | |
| SCHEMBL12634667 | 0.86 | HDAC3 (0.51) | HDAC3HDAC1HDAC2NCOR2CTSL | |
| SCHEMBL8089460 | 0.86 | HDAC3 (0.51) | HDAC3HDAC1HDAC2NCOR2CTSL | |
| SCHEMBL5736847 | 0.86 | HDAC3 (0.51) | HDAC3HDAC1HDAC2NCOR2CTSL | |
| SCHEMBL19615968 | 0.86 | HDAC3 (0.51) | HDAC3HDAC1HDAC2NCOR2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808027-A | ANTISENSE AGENTS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-15 | — | — | US | disclosed |