SCHEMBL30940776

SCHEMBL30940776

CC(C)(C)OC(=O)N(CCCN)CCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MC5R P33032 2/20 0.46
MC3R P41968 2/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.44
MAOA P21397 1/20 0.44
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MC4R P32245 1/20 0.43
HDAC3 O15379 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC2 Q92769 1/20 0.42
NCOR2 Q9Y618 1/20 0.42
ALOX5 P09917 1/20 0.41
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8583347 0.92 MAOA (0.47) MC5RMC3RL3MBTL1MAOAMC4R
SCHEMBL2260891 0.92 MEN1 (0.45) CA12CA1CA2CA4L3MBTL1
SCHEMBL7971622 0.90 MC5R (0.46) MC5RMC3RL3MBTL1MAOAMEN1
SCHEMBL31618024 0.90 PPARG (0.47) CA12CA1CA2CA4
SCHEMBL25047708 0.88 HDAC3 (0.48) CA12CA1CA2CA4L3MBTL1
SCHEMBL8679115 0.88 HDAC3 (0.51) MC5RMC3RL3MBTL1MC4RHDAC3
SCHEMBL25046666 0.88 L3MBTL1 (0.45) L3MBTL1MEN1NPC1RAB9AKMT2A
SCHEMBL25048652 0.87 FDFT1 (0.47)
SCHEMBL30941261 0.87 FDFT1 (0.47)
SCHEMBL25047643 0.87 CA12 (0.43) CA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188110-A1 SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2025-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250188110-A1 SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION KMT5A, KMT5B, KMT5C MC5R 2371/4885MC3R 2220/4885CA12 4281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.