SCHEMBL8679118

SCHEMBL8679118

CCCCOC(=O)NNC(=O)Oc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 7/20 0.57
SMN1; SMN2 Q16637 4/20 0.52
CYP1A2 P05177 2/20 0.52
CYP2C19 P33261 2/20 0.52
TSHR P16473 4/20 0.52
ALDH1A1 P00352 3/20 0.52
TDP1 Q9NUW8 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
MEN1 O00255 1/20 0.50
MAPT P10636 1/20 0.50
THRB P10828 1/20 0.50
HPGD P15428 1/20 0.50
KMT2A Q03164 1/20 0.50
MAPK1 P28482 2/20 0.49
CYP3A4 P08684 1/20 0.49
LMNA P02545 2/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
ESR1 P03372 1/20 0.47
CYP2D6 P10635 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9267402 0.83 GAA (0.62) FAAHSMN1; SMN2CYP1A2CYP2C19TSHR
SCHEMBL15268216 0.82 MGLL (0.64)
SCHEMBL10565870 0.81 FAAH (0.54) FAAHCYP1A2CYP2C19TSHRALDH1A1
SCHEMBL8679113 0.81 TDP1 (0.54) FAAHSMN1; SMN2CYP1A2CYP2C19TSHR
SCHEMBL29791409 0.80 FAAH (0.50) FAAHSMN1; SMN2CYP1A2CYP2C19TSHR
SCHEMBL730122 0.80 TSHR (0.56) FAAHTSHRALDH1A1TDP1L3MBTL1
SCHEMBL15241168 0.79 FAAH (0.58) FAAHALDH1A1MEN1MAPTTHRB
SCHEMBL1625209 0.79 GAA (0.71) SMN1; SMN2CYP1A2CYP2C19TSHRALDH1A1
SCHEMBL16824229 0.79 EPHX1 (0.59) SMN1; SMN2CYP1A2CYP2C19TSHRALDH1A1
SCHEMBL9323400 0.79 TSHR (0.54) FAAHTSHRALDH1A1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5728832-A FOR USE IN A COLOR FORMING PRESSURE SENSITIVE OR HEAT SENSITIVE PAPER FUJI PHOTO FILM CO., LTD. (JP) 1998-03-17 US claimed