Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679934 | 0.85 | CD274 (0.65) | CD274PDCD1GABRA1GABRB2KMT2A | |
| Ammonia Solution, Strong SCHEMBL9346396 | 0.79 | CD274 (0.47) | CD274PDCD1PTGS1ALDH1A1ESR2 | |
| SCHEMBL8679266 | 0.79 | CD274 (0.50) | CD274PDCD1KMT2APTGS1SMN1; SMN2 | |
| SCHEMBL9792869 | 0.77 | PDCD1 (0.54) | CD274PDCD1PTGS1ALDH1A1HPGD | |
| SCHEMBL4630258 | 0.76 | KMT2A (0.60) | CD274PDCD1GABRA1GABRB2ADORA3 | |
| Ammonia Solution, Strong SCHEMBL2967636 | 0.76 | CD274 (0.47) | CD274PDCD1PTGS1ALDH1A1ESR2 | |
| SCHEMBL9342239 | 0.76 | PDCD1 (0.47) | CD274PDCD1ADORA3ADORA2AADORA1 | |
| SCHEMBL11212391 | 0.76 | PDCD1 (0.47) | CD274PDCD1PTGS1HPGDSMN1; SMN2 | |
| SCHEMBL3031707 | 0.74 | KMT2A (0.43) | GABRA1GABRB2ADORA3ADORA2AADORA2B | |
| SCHEMBL11200440 | 0.74 | PDCD1 (0.46) | CD274PDCD1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817251-A | AROMATIC HYDROCARBON LUBRICANT | NIPPON OIL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5711895-A | Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group | NIPPON OIL CO., LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0717098-A2 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON OIL CO. LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |