Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD4 | P01730 | 2/20 | 0.59 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.59 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4114419 | 0.82 | CD4 (0.84) | CD4SORT1KDM4EALDH1A1POLB | |
| SCHEMBL4119590 | 0.76 | ALDH1A1 (0.64) | HTR7KDM4EALDH1A1TSHRTMEM97 | |
| Hydrochloric Acid SCHEMBL7621278 | 0.75 | ALDH1A1 (0.62) | HTR7KDM4EALDH1A1TSHRTMEM97 | |
| SCHEMBL7616547 | 0.75 | CD4 (1.00) | CD4SORT1ALDH1A1POLBTSHR | |
| SCHEMBL21361470 | 0.71 | CD4 (0.86) | CD4SORT1MAPTALDH1A1TSHR | |
| SCHEMBL13925215 | 0.71 | CD4 (0.89) | CD4SORT1ALDH1A1TSHRNPSR1 | |
| SCHEMBL4109293 | 0.70 | CD4 (0.89) | CD4SORT1KDM4EALDH1A1POLB | |
| SCHEMBL4103052 | 0.70 | CD4 (0.88) | CD4SORT1ALDH1A1TSHRNPSR1 | |
| SCHEMBL21361554 | 0.70 | HPGD (0.46) | MAPTKDM4EALDH1A1POLBTSHR | |
| SCHEMBL13925191 | 0.70 | CD4 (0.70) | CD4SORT1ALDH1A1TSHRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809504-A4 | ANTI-VIRAL TRIAZA COMPOUNDS | UNIV NEW YORK STATE RES FOUND (US) | 1998-11-04 | — | — | EP | disclosed |
| EP-0809504-A1 | ANTI-VIRAL TRIAZA COMPOUNDS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025167-A1 | ANTI-VIRAL TRIAZA COMPOUNDS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1996-08-22 | — | — | WO | disclosed |