Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679767 | 0.74 | CDK5 (0.34) | SRD5A1CDK5CDK5R1MBOAT4GRIN1 | |
| SCHEMBL8065726 | 0.74 | SRD5A1 (0.40) | SRD5A1 | |
| SCHEMBL8065728 | 0.74 | SRD5A1 (0.40) | SRD5A1 | |
| SCHEMBL8680375 | 0.73 | GRIN1 (0.36) | SRD5A1GRIN1GRIN2B | |
| SCHEMBL8679342 | 0.73 | SRD5A1 (0.37) | SRD5A1CDK5CDK5R1MBOAT4GRIN1 | |
| SCHEMBL8075950 | 0.73 | SRD5A1 (0.55) | SRD5A1 | |
| SCHEMBL8075952 | 0.73 | SRD5A1 (0.55) | SRD5A1 | |
| SCHEMBL8007057 | 0.71 | SRD5A1 (0.37) | SRD5A1CDK5CDK5R1MBOAT4ALDH1A1 | |
| SCHEMBL8076029 | 0.71 | NR1I3 (0.47) | CDK5CDK5R1GRIN1GRIN2BCYP19A1 | |
| SCHEMBL8018783 | 0.70 | SRD5A1 (0.36) | SRD5A1CDK5CDK5R1MBOAT4GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998009632-A1 | METHODS AND COMPOSITIONS FOR TREATING PRETERM LABOR | MERCK & CO., INC. (US) | 1998-03-12 | — | — | WO | claimed |