Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338002 | 0.90 | TSHR (0.88) | TSHRHPGDCYP3A4TDP1ATM | |
| Acrylic Acid SCHEMBL8679384 | 0.88 | TSHR (0.67) | TSHRHPGDTHRBCYP3A4TDP1 | |
| Acrylic Acid Ethyl Ester SCHEMBL9863764 | 0.86 | TSHR (0.81) | TSHRHPGDCYP3A4TDP1ATM | |
| SCHEMBL8680403 | 0.86 | TSHR (0.81) | TSHRHPGDTHRBCYP3A4TDP1 | |
| Acrylic Acid SCHEMBL3844152 | 0.86 | TSHR (0.81) | TSHRHPGDCYP3A4TDP1ATM | |
| SCHEMBL17139830 | 0.86 | TSHR (0.81) | TSHRHPGDCYP3A4TDP1ATM | |
| Acrylic Acid SCHEMBL7263337 | 0.86 | TSHR (0.81) | TSHRHPGDCYP3A4TDP1ATM | |
| SCHEMBL8213029 | 0.86 | TSHR (0.85) | TSHRHPGDCYP3A4TDP1ATM | |
| SCHEMBL7627062 | 0.84 | TSHR (0.83) | TSHRHPGDCYP3A4TDP1ATM | |
| SCHEMBL3401565 | 0.84 | TSHR (0.83) | TSHRHPGDCYP3A4TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820478-A1 | WATERBORNE POLYMERS HAVING PENDANT ALLYL GROUPS | EASTMAN CHEMICAL COMPANY (US) | 1998-01-28 | — | — | EP | disclosed |