SCHEMBL8679474

SCHEMBL8679474

CCC(=O)C(C(=O)O)(C(=O)CC)C(=O)CC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.44
ALDH1A1 P00352 5/20 0.37
TDP1 Q9NUW8 2/20 0.37
TSHR P16473 3/20 0.35
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
DRD2 P14416 1/20 0.32
OPRM1 P35372 1/20 0.32
DRD3 P35462 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
THRB P10828 1/20 0.31
KMT2A Q03164 1/20 0.31
FFAR1 O14842 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4731978 0.94 FFAR3 (0.44) FFAR3ALDH1A1TDP1TSHRCYP2D6
SCHEMBL288538 0.80 TDP1 (0.39) FFAR3TDP1
SCHEMBL16336541 0.75 ALDH1A1 (0.44) FFAR3ALDH1A1TDP1TSHR
SCHEMBL959564 0.75 ALDH1A1 (0.44) FFAR3ALDH1A1TDP1TSHR
SCHEMBL1022151 0.73 FFAR3 (0.42) FFAR3ALDH1A1TDP1TSHRCYP2D6
SCHEMBL4953246 0.73 FFAR3 (0.42) FFAR3ALDH1A1TDP1TSHRCYP2D6
SCHEMBL911270 0.73 FFAR3 (0.42) FFAR3ALDH1A1TDP1TSHRCYP2D6
SCHEMBL14370458 0.71 ALDH1A1 (0.45) FFAR3ALDH1A1TDP1TSHRCYP2D6
SCHEMBL5604100 0.71 FFAR3 (0.40) FFAR3ALDH1A1TDP1TSHRCYP2D6
SCHEMBL13545111 0.71 FFAR3 (0.40) FFAR3ALDH1A1TDP1TSHRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5766835-A WITH BACKING LAYER WHICH IS A TRANSPARENT MAGNETIC RECORDING LAYER CONTAINING A DI- OR POLYISOCYANATE CROSSLINKING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1998-06-16 US disclosed
EP-0603582-B1 Silver halide photographic material including a magnetic recording layer FUJI PHOTO FILM CO LTD (JP) 1997-02-05 EP disclosed
EP-0603582-A1 Silver halide photographic material including a magnetic recording layer FUJI PHOTO FILM CO., LTD. (JP) 1994-06-29 EP disclosed