Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731978 | 0.85 | FFAR3 (0.44) | TDP1FFAR3 | |
| SCHEMBL8679474 | 0.80 | FFAR3 (0.44) | TDP1FFAR3 | |
| SCHEMBL5547489 | 0.74 | TDP1 (0.41) | TDP1FFAR3 | |
| SCHEMBL407289 | 0.70 | TDP1 (0.47) | TDP1FFAR3 | |
| SCHEMBL1948056 | 0.69 | TDP1 (0.45) | TDP1 | |
| SCHEMBL93369 | 0.68 | — | — | |
| SCHEMBL11444482 | 0.67 | TDP1 (0.43) | TDP1FFAR3 | |
| SCHEMBL14666320 | 0.67 | TDP1 (0.43) | TDP1FFAR3 | |
| SCHEMBL15658553 | 0.67 | TDP1 (0.43) | TDP1FFAR3 | |
| SCHEMBL28650382 | 0.67 | FAAH (0.43) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9487468-B2 | Methylidene malonate process | OPTMED, INC. (US) | 2016-11-08 | — | — | US | disclosed |
| US-20150203437-A1 | METHYLIDENE MALONATE PROCESS | OPTMED INC. (US) | 2015-07-23 | — | — | US | disclosed |
| US-8993795-B2 | Methylidene malonate process | OPTMED INC (US) | 2015-03-31 | — | — | US | disclosed |
| US-20130008773-A1 | METHYLIDENE MALONATE PROCESS | OPTMED, INC. (US) | 2013-01-10 | — | — | US | disclosed |
| EP-2427422-A1 | IMPROVED METHYLIDENE MALONATE PROCESS | Optmed Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| US-20100286433-A1 | METHYLIDENE MALONATE PROCESS | OPTMED, INC. | 2010-11-11 | — | — | US | disclosed |
| WO-2010129066-A1 | IMPROVED METHYLIDENE MALONATE PROCESS | OPTMED INC. (US) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286433-A1 | METHYLIDENE MALONATE PROCESS | MMAB, ME1, MAL2 | TDP1 4668/4885FFAR3 4357/4885 |
| US-20150203437-A1 | METHYLIDENE MALONATE PROCESS | MMAB, ME1, MAL2 | TDP1 4668/4885FFAR3 4357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.