Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.45 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
| ▸ | GGH | Q92820 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8457126 | 0.75 | GGH (0.44) | FOLH1NAALAD2GGHCYP1A2CYP2C19 | |
| SCHEMBL7649639 | 0.73 | BCHE (0.40) | FOLH1GRM8GRM4NAALAD2BCHE | |
| SCHEMBL7050992 | 0.72 | CYP1A2 (0.36) | FOLH1GRM8GRM4BCHECYP1A2 | |
| SCHEMBL7615307 | 0.72 | BCHE (0.36) | FOLH1GRM8GRM4NAALAD2BCHE | |
| SCHEMBL10372633 | 0.72 | BCHE (0.46) | GRM8GRM4BCHEKDM4EHSD17B10 | |
| SCHEMBL5060196 | 0.71 | CPA3 (0.44) | FOLH1GGH | |
| SCHEMBL7050154 | 0.71 | CYP1A2 (0.37) | GRM8GRM4BCHECYP1A2CYP2C9 | |
| SCHEMBL7651193 | 0.71 | GRM8 (0.47) | GRM8GRM4ANPEPERAP2ERAP1 | |
| SCHEMBL5059853 | 0.71 | GGH (0.36) | FOLH1GRM8GRM4GGHBCHE | |
| SCHEMBL6495705 | 0.71 | BCHE (0.44) | GRM8GRM4BCHEKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998047906-A1 | PHOSPHONIC ACID DERIVATIVES | GUILFORD PHARMACEUTICALS INC. (US) | 1998-10-29 | — | — | WO | claimed |
| WO-1998047906-A1 | PHOSPHONIC ACID DERIVATIVES | GUILFORD PHARMACEUTICALS INC. (US) | 1998-10-29 | — | — | WO | disclosed |