Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.83 |
| ▸ | MTOR | P42345 | 2/20 | 0.83 |
| ▸ | THRB | P10828 | 1/20 | 0.83 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.83 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.83 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.83 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8680234 | 1.00 | LMNA (0.83) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL11120331 | 0.96 | LMNA (0.81) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL14565251 | 0.96 | LMNA (0.81) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL30115 | 0.96 | LMNA (0.81) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL12031031 | 0.96 | LMNA (0.81) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL30116 | 0.96 | LMNA (0.81) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL14580391 | 0.96 | LMNA (0.81) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL30117 | 0.96 | LMNA (0.81) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL21423095 | 0.96 | LMNA (0.81) | LMNAMTORTHRBMDM2NCOA1 | |
| Phosphoric Acid SCHEMBL20769293 | 0.92 | LMNA (0.74) | LMNAMTORTHRBMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780607-A | PYRANOSYL NUCLEOSIDE MONOMER UNITS CONNECTED BY AMIDE LINKAGES | HOFFMANN-LA ROCHE INC. (US) | 1998-07-14 | — | — | US | disclosed |