Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.81 |
| ▸ | MTOR | P42345 | 2/20 | 0.81 |
| ▸ | THRB | P10828 | 1/20 | 0.81 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.81 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.81 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.81 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30116 | 1.00 | LMNA (0.81) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL21423095 | 1.00 | LMNA (0.81) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL11120331 | 1.00 | LMNA (0.81) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL12031031 | 1.00 | LMNA (0.81) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL14565251 | 1.00 | LMNA (0.81) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL14580391 | 1.00 | LMNA (0.81) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL30117 | 1.00 | LMNA (0.81) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL8680244 | 0.96 | LMNA (0.83) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL8680234 | 0.96 | LMNA (0.83) | LMNAMTORTHRBMDM2NCOA1 | |
| Phosphoric Acid SCHEMBL21465076 | 0.95 | LMNA (0.74) | LMNAMTORTHRBMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 444 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250263678-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF RNA | REJUVENATION TECHNOLOGIES, INC. (US) | 2025-08-21 | — | — | US | claimed |
| US-12343420-B2 | Stabilized polyribonucleotide coding for an elastic fibrous protein | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2025-07-01 | — | — | US | claimed |
| EP-4379052-A2 | MRNA PURIFICATION BY TANGENTIAL FLOW FILTRATION | Ethris GmbH (DE) | 2024-06-05 | — | — | EP | claimed |
| EP-4306643-A2 | PLASMID CONTAINING A SEQUENCE ENCODING AN MRNA WITH A SEGMENTED POLY(A) TAIL | ethris GmbH (DE) | 2024-01-17 | — | — | EP | claimed |
| EP-4271389-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF RNA | Rejuvenation Technologies Inc. (US) | 2023-11-08 | — | — | EP | claimed |
| US-11479768-B2 | ATP-binding cassette family coding polyribonucleotides and formulations thereof | ETHRIS GMBH (DE) | 2022-10-25 | — | — | US | claimed |
| US-20220249346-A1 | STABILIZED POLYRIBONUCLEOTIDE CODING FOR AN ELASTIC FIBROUS PROTEIN | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2022-08-11 | — | — | US | claimed |
| WO-2022147039-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF RNA | REJUVENATION TECHNOLOGIES INC. (US) | 2022-07-07 | — | — | WO | claimed |
| US-20220002737-A1 | ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN EXPRESSION | CUREVAC AG (DE) | 2022-01-06 | — | — | US | claimed |
| EP-3913054-A2 | ATP-BINDING CASSETTE FAMILY CODING POLYRIBONUCLEOTIDES AND FORMULATIONS THEREOF | Ethris GmbH (DE) | 2021-11-24 | — | — | EP | claimed |
| WO-2014209979-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. (US) | 2014-12-31 | — | — | WO | claimed |
| WO-2013082515-A2 | NUCLEIC ACID APTAMERS DIRECTED TO SURFACE RECEPTORS AND METHODS OF USE | DUKE UNIVERSITY (US) | 2013-06-06 | — | — | WO | claimed |
| EP-2399588-A1 | Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase | Merck Sharp & Dohme Corp. (US) | 2011-12-28 | — | — | EP | claimed |
| US-7812001-B2 | RNA aptamers and methods for identifying the same | DUKE UNIVERSITY (US) | 2010-10-12 | — | — | US | claimed |
| EP-1539188-A2 | NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RNA-DEPENDENT RNA VIRAL POLYMERASE | Merck & Co., Inc. (US) | 2005-06-15 | — | — | EP | claimed |
| US-20040110717-A1 | Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase | MERCK SHARP & DOHME LLC | 2004-06-10 | — | — | US | claimed |
| EP-1333090-A1 | Prionprotein-specific aptamers | NascaCell GmbH (DE) | 2003-08-06 | — | — | EP | claimed |
| US-6528640-B1 | Of given formula; can use to inhibit HER2/neu/ ErbB2 gene expression; anticarcinogenic agents | RIBOZYME PHARMACEUTICALS, INCORPORATED | 2003-03-04 | — | — | US | claimed |
| WO-2002057425-A2 | NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RNA-DEPENDENT RNA VIRAL POLYMERASE | MERCK & CO., INC. (US) | 2002-07-25 | — | — | WO | claimed |
| US-5856085-A | INCUBATION SINGLE-STRANDED NUCLEIC ACIDS; AMPLIFICATION; ANALYZING | THE PENN STATE RESEARCH FOUNDATION (US) | 1999-01-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11479768-B2 | ATP-binding cassette family coding polyribonucleotides and formulations thereof | ABCD3, ABCC3, ABCF1 | LMNA 1642/4885MTOR 4866/4885THRB 4000/4885 |
| US-20250263678-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF RNA | RNASE1, POLRMT, TERT | LMNA 233/4885MTOR 4147/4885THRB 897/4885 |
| US-20040110717-A1 | Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase | NSUN2, NSUN3, POLRMT | LMNA 3403/4885MTOR 2546/4885THRB 4769/4885 |
| US-20220002737-A1 | ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN EXPRESSION | CPSF6, CPSF1, RNMT | LMNA 1042/4885MTOR 2571/4885THRB 3421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.