Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27318923 | 0.93 | HSD17B3 (0.63) | HSD17B3MAPTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL27463336 | 0.89 | HSD17B3 (0.43) | HSD17B3L3MBTL1MAPTLMNATDP1 | |
| SCHEMBL8402206 | 0.85 | HSD17B3 (0.51) | HSD17B3L3MBTL1MAPTLMNATDP1 | |
| SCHEMBL11631620 | 0.84 | KMT2A (0.59) | L3MBTL1LMNARAB9AALDH1A1CYP1A2 | |
| SCHEMBL12949980 | 0.83 | HSD17B3 (0.50) | HSD17B3L3MBTL1MAPTLMNATDP1 | |
| SCHEMBL31556191 | 0.82 | L3MBTL1 (0.54) | HSD17B3L3MBTL1MAPTLMNATDP1 | |
| SCHEMBL10622910 | 0.81 | CYP1A2 (0.44) | L3MBTL1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL7049792 | 0.81 | ALDH1A1 (0.50) | L3MBTL1MAPTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL31556197 | 0.80 | CA12 (0.56) | HSD17B3L3MBTL1MAPTLMNATDP1 | |
| SCHEMBL8399254 | 0.80 | MAPT (0.61) | HSD17B3L3MBTL1MAPTLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741821-A | PHENOLIC ENZYME INHIBITORS | THE UNIVERSITY OF SYDNEY (AU) | 1998-04-21 | — | — | US | disclosed |
| WO-1994028886-A1 | USE OF NATURAL PRODUCTS AND RELATED SYNTHETIC COMPOUNDS FOR THE TREATMENT OF CARDIOVASCULAR DISEASE | THE UNIVERSITY OF SYDNEY (AU) | 1994-12-22 | — | — | WO | disclosed |