SCHEMBL8680690

SCHEMBL8680690

CN(C)Cc1ccccc1CO

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 11/20 0.53
SLC6A2 P23975 8/20 0.51
SLC6A3 Q01959 3/20 0.47
ALDH1A1 P00352 4/20 0.47
TSHR P16473 2/20 0.47
KDM4E B2RXH2 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C19 P33261 1/20 0.47
HSD17B10 Q99714 1/20 0.47
LMNA P02545 2/20 0.44
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
THRB P10828 1/20 0.44
G6PD P11413 1/20 0.44
PABPC1 P11940 1/20 0.44
HKDC1 Q2TB90 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29993827 1.00 SLC6A4 (0.53) SLC6A4SLC6A2SLC6A3ALDH1A1TSHR
Alcohol SCHEMBL28875867 0.88 SLC6A4 (0.53) SLC6A4SLC6A2SLC6A3ALDH1A1TSHR
SCHEMBL125255 0.87 ALDH1A1 (0.57) SLC6A4SLC6A2SLC6A3ALDH1A1TSHR
SCHEMBL29729780 0.87 ALDH1A1 (0.57) SLC6A4SLC6A2SLC6A3ALDH1A1TSHR
SCHEMBL6772494 0.85 SLC6A4 (0.49) SLC6A4SLC6A2ALDH1A1TSHRKDM4E
SCHEMBL8677184 0.82 SLC6A4 (0.48) SLC6A4SLC6A2SLC6A3ALDH1A1TSHR
SCHEMBL11632956 0.80 SLC6A4 (0.74) SLC6A4SLC6A2SLC6A3ALDH1A1LMNA
SCHEMBL29366632 0.79 APOBEC3G (0.60) ALDH1A1TSHRCYP2D6LMNAGAA
SCHEMBL41139 0.79 APOBEC3G (0.60) ALDH1A1TSHRCYP2D6LMNAGAA
SCHEMBL13360178 0.79 HSD17B3 (0.43) SLC6A4ALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001838-A1 NANOMATERIALS GUIDE THERAPEUTICS LLC (US) 2026-01-01 US disclosed
US-12435035-B2 Nanomaterials GUIDE THERAPEUTICS, LLC (US) 2025-10-07 US disclosed
US-20230285581-A1 RIFAMYCIN ANALOGS AND ANTIBODY-DRUG CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2023-09-14 US disclosed
US-11666658-B2 Rifamycin analogs and antibody-drug conjugates thereof Regeneran Pharmaceuticals, Inc. (US) 2023-06-06 US disclosed
EP-4103542-A1 NANOMATERIALS Guide Therapeutics, LLC (US) 2022-12-21 EP disclosed
CN-115175894-A Nano material 盖德治疗有限责任公司 2022-10-11 CN disclosed
EP-3897841-A1 RIFAMYCIN ANALOGS AND ANTIBODY-DRUG CONJUGATES THEREOF Regeneron Pharmaceuticals, Inc. (US) 2021-10-27 EP disclosed
CN-113226470-A Rifamycin analogs and antibody-drug conjugates thereof 瑞泽恩制药公司 2021-08-06 CN disclosed
US-20210230112-A1 NANOMATERIALS GUIDE THERAPEUTICS, LLC 2021-07-29 US disclosed
US-20200368361-A1 RIFAMYCIN ANALOGS AND ANTIBODY-DRUG CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2020-11-26 US disclosed
WO-2020132483-A1 RIFAMYCIN ANALOGS AND ANTIBODY-DRUG CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2020-06-25 WO disclosed
US-5723398-A CATALYST OF METAL CYCLOPENTADIENYL COMPLEX FOR POLYMERIZATION THE DOW CHEMICAL COMPANY (US) 1998-03-03 US disclosed
US-5494874-A TITANIUM COMPLEXES WITH A COCATALYST AS POLYMERIZATION CATALYSTS THE DOW CHEMICAL COMPANY (US) 1996-02-27 US disclosed
US-5374696-A Catalyzing the addition polymerization in presence of titanium metal complexes with cocatalysts THE DOW CHEMICAL COMPANY (US) 1994-12-20 US disclosed
EP-0270091-B1 IMIDAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION OF THE SAME, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, THE USE OF THE SAME FOR THE MANUFACTURE OF MEDICAMENTS OF THERAPEUTIC VALUE, AND INTERMEDIATES FORMED DURING SAID PROCESSES TANABE SEIYAKU CO., LTD. (JP) 1992-11-11 EP disclosed
US-5053417-A Antiulcer agents TANABE SEIYAKU CO., LTD. (JP) 1991-10-01 US disclosed
US-5002945-A Antiulcer agents TANABE SEIYAKU CO. LTD. (JP) 1991-03-26 US disclosed
US-4996217-A Antiulcer agents TANABE SEIYAKU COMPANY, LTD. (JP) 1991-02-26 US disclosed
EP-0270091-A1 Imidazole derivatives, processes for the preparation of the same, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments of therapeutic value, and intermediates formed during said processes TANABE SEIYAKU CO., LTD. (JP) 1988-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210230112-A1 NANOMATERIALS NPC1, NPC1L1, FABP1 SLC6A4 2588/4885SLC6A2 1535/4885SLC6A3 2481/4885
US-20200368361-A1 RIFAMYCIN ANALOGS AND ANTIBODY-DRUG CONJUGATES THEREOF ASGR1, CUTA, SRPRA SLC6A4 3414/4885SLC6A2 2695/4885SLC6A3 3296/4885
US-20260001838-A1 NANOMATERIALS SLC10A1, NPC1L1, FABP1 SLC6A4 1940/4885SLC6A2 791/4885SLC6A3 2617/4885
US-11666658-B2 Rifamycin analogs and antibody-drug conjugates thereof ASGR1, CUTA, SRPRA SLC6A4 3414/4885SLC6A2 2695/4885SLC6A3 3296/4885
US-12435035-B2 Nanomaterials NPC1, NPC1L1, FABP1 SLC6A4 2588/4885SLC6A2 1535/4885SLC6A3 2481/4885
US-20230285581-A1 RIFAMYCIN ANALOGS AND ANTIBODY-DRUG CONJUGATES THEREOF ASGR1, CUTA, SRPRA SLC6A4 3414/4885SLC6A2 2695/4885SLC6A3 3296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.