SCHEMBL8680715

SCHEMBL8680715

NNS(=O)(=O)CCCC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.43
SLC22A6 Q4U2R8 1/20 0.43
TSHR P16473 3/20 0.42
THRB P10828 2/20 0.42
BLM P54132 2/20 0.42
KMT2A Q03164 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
CYP1A2 P05177 2/20 0.42
APEX1 P27695 1/20 0.42
GABRR3 A8MPY1 1/20 0.42
GABRP O00591 1/20 0.42
GABRD O14764 1/20 0.42
HDAC3 O15379 1/20 0.42
GABBR2 O75899 1/20 0.42
GABRA1 P14867 1/20 0.42
GABRB1 P18505 1/20 0.42
GABRG2 P18507 1/20 0.42
GABRR1 P24046 1/20 0.42
GABRB3 P28472 1/20 0.42
GABRR2 P28476 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27872399 0.86 APEX1 (0.52) LMNASLC22A6TSHRTHRBBLM
SCHEMBL18560320 0.80
SCHEMBL19153270 0.80 PAOX (0.41) LMNAKMT2AMEN1ALDH1A1MAPT
SCHEMBL26650508 0.77 LMNA (0.43) LMNASLC22A6TSHRKMT2AAPEX1
Adipic Acid SCHEMBL18343453 0.76 LMNA (0.55) LMNASLC22A6TSHRTHRBBLM
SCHEMBL29678254 0.75 LMNA (0.41) LMNASLC22A6TSHRTHRBBLM
SCHEMBL393044 0.73 LMNA (0.50) LMNASLC22A6TSHRTHRBBLM
SCHEMBL21110663 0.72 CA1 (0.37) LMNASLC22A6TSHRTHRBBLM
SCHEMBL19049767 0.72 TSHR (0.48) LMNASLC22A6TSHRTHRBKMT2A
SCHEMBL19049766 0.72 TSHR (0.48) LMNASLC22A6TSHRTHRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5757408-A PRINTING IMAGE ON SUBSTRATE COATED WITH AMINO-ACID DERIVATIVE ADDITIVE; QUICK DRYING OF INK, OPTICAL DENSITY, NONCURLING XEROX CORPORATION (US) 1998-05-26 US claimed
US-5683793-A Ink jet transparencies XEROX CORPORATION (US) 1997-11-04 US claimed
US-5589277-A INK JET PRINTING, AQUEOUS INKS, FAST DRYING XEROX CORPORATION (US) 1996-12-31 US claimed
EP-0667246-A1 Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds XEROX CORPORATION (US) 1995-08-16 EP claimed
CN-102712676-B There is the peptidomimetic that the template of CCR10 antagonistic activity is fixing 波利弗尔股份公司 2016-10-26 CN disclosed
CN-102712676-A Template-fixed peptidomimetics with CCR10 antagonistic activty POLYPHOR AG 2012-10-03 CN disclosed