SCHEMBL393044

SCHEMBL393044

NS(=O)(=O)CCCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.50
SLC22A6 Q4U2R8 2/20 0.50
TSHR P16473 3/20 0.48
THRB P10828 2/20 0.48
BLM P54132 2/20 0.48
KMT2A Q03164 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
APEX1 P27695 1/20 0.48
GABRR3 A8MPY1 1/20 0.48
GABRP O00591 1/20 0.48
GABRD O14764 1/20 0.48
HDAC3 O15379 1/20 0.48
GABBR2 O75899 1/20 0.48
CYP1A2 P05177 1/20 0.48
GABRA1 P14867 1/20 0.48
GABRB1 P18505 1/20 0.48
GABRG2 P18507 1/20 0.48
GABRR1 P24046 1/20 0.48
GABRB3 P28472 1/20 0.48
GABRR2 P28476 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2026119 0.92 LMNA (0.55) LMNASLC22A6TSHRTHRBBLM
SCHEMBL11097531 0.90 TSHR (0.57) LMNASLC22A6TSHRTHRBBLM
SCHEMBL7606907 0.90 TSHR (0.57) LMNASLC22A6TSHRTHRBBLM
SCHEMBL1463490 0.83
SCHEMBL21110663 0.82 CA1 (0.37) LMNASLC22A6TSHRTHRBBLM
SCHEMBL3169639 0.81 ARG1 (0.32) LMNATSHRBLMKMT2AAPEX1
Succinic Acid SCHEMBL29243143 0.78 GPR84 (0.56) LMNASLC22A6TSHRBLMKMT2A
Succinic Acid SCHEMBL29243141 0.78 GPR84 (0.56) LMNASLC22A6TSHRBLMKMT2A
SCHEMBL11330927 0.78 APEX1 (0.68) LMNASLC22A6TSHRTHRBBLM
SCHEMBL12666039 0.77 ARG1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 416 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117285446-A Synthesis method of 4-sulfamoyl butyric acid 成都普康生物科技有限公司 2023-12-26 CN claimed
CN-107200905-B A kind of micro-elasticity plastics sheep bed and its preparation method and application 山东阳春羊奶乳业有限公司 2019-08-13 CN claimed
CN-108703954-A A kind of preparation method of Ezetimibe piece 广州维奥康药业科技有限公司 2018-10-26 CN claimed
CN-105254687-B A kind of synthetic method of amikacin 齐鲁天和惠世制药有限公司 2018-06-19 CN claimed
CN-107200905-A A kind of micro-elasticity plastics sheep bed and its preparation method and application 山东阳春羊奶乳业有限公司 2017-09-26 CN claimed
CN-102216279-A Phenyl pyrimidone compounds, pharmaceutical compositions, preparation methods and uses thereof TOPHARMAN SHANGHAI CO LTD 2011-10-12 CN claimed
EP-1174151-B1 THERAPEUTIC TREATMENT OF EOSINOPHILIA USING CHYMASE INHIBITORS AS THE ACTIVE INGREDIENT DAIICHI ASUBIO PHARMA CO LTD (JP) 2007-01-24 EP claimed
US-7166696-B2 Solid phase synthesis supports and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-01-23 US claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
US-20040265899-A1 Solid phase synthesis supports and methods 3M INNOVATIVE PROPERTIES COMPANY 2004-12-30 US claimed
US-6787635-B2 azlactone-functionalized support such as a crosslinked polymer containing an alkenyl azlactone; use making combinatorial libraries 3M INNOVATIVE PROPERTIES COMPANY 2004-09-07 US claimed
US-6677344-B2 Chymase inhibitor for the treatment of eosinophilia DAIICHI SUNTORY PHARMA CO., LTD. (JP) 2004-01-13 US claimed
EP-1373167-A2 SOLID PHASE SYNTHESIS SUPPORTS AND METHODS 3M Innovative Properties Company (US) 2004-01-02 EP claimed
WO-2003068806-A1 SOLID PHASE PEPTIDE SYNTHESIS ON SILICA JOHNSON MATTHEY PLC (GB) 2003-08-21 WO claimed
US-6500835-B2 FOR PROPHYLAXIS AND THERAPY OF FIBROSIS INVOLVING EXTRACELLULAR MATRIX DYSBOLISM HAVING A CHYMASE INHIBITOR AS AN EFFECTIVE INGREDIENT; SIDE EFFECT REDUCTION SUNTORY LIMITED (JP) 2002-12-31 US claimed
US-20020173051-A1 Solid phase synthesis supports and methods 3M INNOVATIVE PROPERTIES COMPANY 2002-11-21 US claimed
WO-2002081078-A2 SOLID PHASE SYNTHESIS SUPPORTS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-10-17 WO claimed
EP-4731269-A1 RADIOLABELED COMPOUND FOR USE IN A METHOD OF TREATING CARBONIC ANHYDRASE IX POSITIVE DISEASES Debiopharm International SA (CH) 2026-04-29 EP disclosed
US-5192774-A SUBSTITUTED ACETAMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND ANTIULCER DRUG CONTAINING SAME ZERIA PHARMACEUTICAL CO., LTD. (JP) 1993-03-09 US disclosed
EP-0404949-A1 SUBSTITUTED ACETAMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND ANTIULCER DRUG CONTAINING SAME ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020173051-A1 Solid phase synthesis supports and methods FES, LSS, CCNK LMNA 1506/4885SLC22A6 2246/4885TSHR 3025/4885
US-20040265899-A1 Solid phase synthesis supports and methods FES, LSS, CCNK LMNA 1506/4885SLC22A6 2246/4885TSHR 3025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.