Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812171 | 0.88 | KCNMA1 (0.46) | KCNMA1SMN1; SMN2TSHRKMT2AATM | |
| SCHEMBL5086786 | 0.88 | KCNMA1 (0.53) | KCNMA1SMN1; SMN2TSHRKMT2AATM | |
| SCHEMBL9627040 | 0.86 | KCNMA1 (0.46) | KCNMA1SMN1; SMN2TSHRKMT2AATM | |
| SCHEMBL4963816 | 0.84 | KCNMA1 (0.51) | KCNMA1SMN1; SMN2TSHRKMT2AATM | |
| SCHEMBL9437945 | 0.82 | KCNMA1 (0.57) | KCNMA1SMN1; SMN2TSHRKMT2AATM | |
| SCHEMBL6337162 | 0.82 | KCNMA1 (0.45) | KCNMA1SMN1; SMN2TSHRKMT2AATM | |
| SCHEMBL3179989 | 0.81 | KCNMA1 (0.51) | KCNMA1SMN1; SMN2TSHRKMT2AATM | |
| SCHEMBL6528132 | 0.80 | KCNMA1 (0.53) | KCNMA1SMN1; SMN2TSHRKMT2AATM | |
| SCHEMBL9437990 | 0.80 | KCNMA1 (0.41) | KCNMA1SMN1; SMN2TSHRKMT2AATM | |
| SCHEMBL5080637 | 0.80 | KCNMA1 (0.47) | KCNMA1SMN1; SMN2TSHRKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744527-A | SHELL, CORE POLYMER | POLYPLASTICS CO., LTD. (JP) | 1998-04-28 | — | — | US | disclosed |