Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8680993 | 1.00 | EDNRA (0.44) | EDNRACAPN1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7437245 | 0.89 | CAPN1 (0.46) | CAPN1CTSSCTSK | |
| SCHEMBL7437237 | 0.89 | CAPN1 (0.46) | CAPN1CTSSCTSK | |
| SCHEMBL8681311 | 0.89 | ALDH1A1 (0.44) | CAPN1ALDH1A1HPGDSMN1; SMN2PSMB5 | |
| SCHEMBL8680990 | 0.88 | ALDH1A1 (0.40) | EDNRAALDH1A1HPGDSMN1; SMN2PSMB5 | |
| SCHEMBL7303217 | 0.85 | CAPN1 (0.48) | CAPN1PSMB5PSMB1PSMB2CTSL | |
| SCHEMBL7304428 | 0.85 | CAPN1 (0.57) | CAPN1CTSLCTSSCTSK | |
| SCHEMBL7312633 | 0.85 | CAPN1 (0.52) | CAPN1CTSLCTSK | |
| SCHEMBL7307053 | 0.85 | CAPN1 (0.57) | CAPN1CTSLCTSSCTSK | |
| SCHEMBL7430388 | 0.85 | CAPN1 (0.48) | CAPN1PSMB5PSMB1PSMB2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834508-A | PROTEASE ENZYME INHIBITORS; MUSCLE DISORDERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5639783-A | POTENT PROTEASE INHIBITOR FOR TREATING MUSCULAR, NERVOUS SYSTEM DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-17 | — | — | US | disclosed |