Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1242990 | 0.78 | GABRA1 (0.41) | GABRA1GABRB1CA1CA2ALOX15 | |
| SCHEMBL14706184 | 0.74 | GABRA1 (0.67) | GABRA1GABRB1CA1CA2ALOX15 | |
| SCHEMBL7868811 | 0.74 | GABRA1 (0.43) | GABRA1GABRB1CA1CA2ALOX15 | |
| SCHEMBL23845078 | 0.73 | GABRA1 (0.48) | GABRA1GABRB1ALOX15ALOX12LMNA | |
| SCHEMBL29810169 | 0.73 | GABRA1 (0.48) | GABRA1GABRB1CA1CA2ALOX15 | |
| SCHEMBL572969 | 0.73 | GABRA1 (0.48) | GABRA1GABRB1CA1CA2ALOX15 | |
| SCHEMBL25274613 | 0.72 | CA1 (0.45) | GABRA1GABRB1CA1CA2ALOX15 | |
| SCHEMBL11504879 | 0.71 | TRPV1 (0.42) | CA1CA2ALOX15ALOX12LMNA | |
| SCHEMBL16736914 | 0.70 | LMNA (0.58) | GABRA1GABRB1ALOX15ALOX12LMNA | |
| SCHEMBL18272118 | 0.70 | GABRA1 (0.46) | GABRA1GABRB1CA1CA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716443-A | MIXTURES OF POLYDIMETHYLSILOXANE, ANOTHER POLYSILOXANE HAVING MONOMERS CONTAINING AMINOALKYL GROUPS, ORGANIC ACIDS AND AQUEOUS ORGANIC SOLVENTS | TAIHO INDUSTRIES, CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| US-5584917-A | POLYSILOXANE WITH TERT-AMINO GROUP; DURABILITY, ONE STEP TREATMENT | TAIHO INDUSTRIES CO., LTD. (JP) | 1996-12-17 | — | — | US | disclosed |