Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487377 | 0.90 | L3MBTL1 (0.61) | L3MBTL1PSMB5MEN1KMT2ALMNA | |
| SCHEMBL23221689 | 0.88 | PSMB5 (0.60) | L3MBTL1PSMB5MEN1KMT2ALMNA | |
| SCHEMBL21583734 | 0.88 | PSMB5 (0.60) | L3MBTL1PSMB5MEN1KMT2ALMNA | |
| SCHEMBL9237118 | 0.88 | PSMB5 (0.60) | L3MBTL1PSMB5MEN1KMT2ALMNA | |
| SCHEMBL4889588 | 0.86 | LMNA (0.71) | L3MBTL1PSMB5MEN1KMT2ALMNA | |
| SCHEMBL9716670 | 0.86 | LMNA (0.71) | L3MBTL1PSMB5MEN1KMT2ALMNA | |
| SCHEMBL7778087 | 0.86 | LMNA (0.71) | L3MBTL1PSMB5MEN1KMT2ALMNA | |
| SCHEMBL16452917 | 0.86 | LMNA (0.71) | L3MBTL1PSMB5MEN1KMT2ALMNA | |
| SCHEMBL18775045 | 0.86 | PSMB5 (0.60) | PSMB5MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL24832472 | 0.86 | L3MBTL1 (0.53) | L3MBTL1PSMB5MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750696-A | HYPOTENSIVE AGENTS | JAPAN TOBACCO INC. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0656356-A1 | DIOXACYCLOALKANE COMPOUND WITH RENIN-INHIBITING ACTIVITY | JAPAN TOBACCO INC. (JP) | 1995-06-07 | — | — | EP | disclosed |