Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SCN4A | P35499 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SCN1A | P35498 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8682019 | 1.00 | MAOA (0.54) | MAOAHTR2BHTR1AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL7423104 | 0.98 | MAOA (0.52) | MAOAHTR2BHTR1AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL7425092 | 0.98 | MAOA (0.52) | MAOAHTR2BHTR1AADRA2AADRA2B | |
| SCHEMBL1667585 | 0.86 | HTR1A (0.56) | MAOAHTR2BHTR1AADRA2AADRA2B | |
| SCHEMBL27736563 | 0.83 | HTR1A (0.61) | MAOAHTR2BHTR1AADRA2AADRA2B | |
| SCHEMBL6456134 | 0.83 | HTR1A (0.61) | MAOAHTR2BHTR1AADRA2AADRA2B | |
| SCHEMBL7697256 | 0.81 | HTR1A (0.52) | MAOAHTR2BHTR1AADRA2AADRA2B | |
| SCHEMBL7697257 | 0.81 | HTR1A (0.52) | MAOAHTR2BHTR1AADRA2AADRA2B | |
| SCHEMBL5517105 | 0.81 | AAK1 (0.45) | ALDH1A1CYP2D6CYP3A4KDM4E | |
| SCHEMBL27581075 | 0.81 | SMN1; SMN2 (0.48) | MAOAHTR2BHTR1AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811424-A | CONTROL OF DOWNY MILDEW, LATE BLIGHT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-09-22 | — | — | US | disclosed |