Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11334877 | 0.80 | ALDH1A1 (0.35) | ALOX5MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL11099498 | 0.79 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL11188819 | 0.77 | MEN1 (0.34) | ALOX5MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL11092534 | 0.77 | MAPT (0.46) | SMN1; SMN2GAALMNA | |
| SCHEMBL22560034 | 0.77 | MEN1 (0.42) | ALOX5MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL2234874 | 0.77 | GAA (0.44) | ALOX5MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL31663152 | 0.77 | GAA (0.44) | ALOX5MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL4653392 | 0.76 | CYP2D6 (0.36) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8417012 | 0.76 | GAA (0.43) | SMN1; SMN2NPSR1GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL10834103 | 0.76 | MEN1 (0.33) | ALOX5MEN1KMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753661-A | TREATMENT OF NERVOUS SYSTEM, PSYCHOLOGICAL DISORDERS; ANTIDEPRESSANTS | H. LUNDBECK A/S (DK) | 1998-05-19 | — | — | US | disclosed |