Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | ME1 | P48163 | 5/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | ME2 | P23368 | 4/20 | 0.38 |
| ▸ | ME3 | Q16798 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090090 | 0.87 | ALDH1A1 (0.42) | MAPTKDM4EGAALMNAALDH1A1 | |
| SCHEMBL8683030 | 0.77 | ALOX5 (0.42) | GAALMNASMN1; SMN2 | |
| SCHEMBL4714410 | 0.73 | KIF11 (0.46) | MAPTKDM4EGAATDP1KIF11 | |
| SCHEMBL3712105 | 0.70 | KDM4E (0.50) | MAPTKDM4EGAALMNAALDH1A1 | |
| SCHEMBL7041242 | 0.69 | MAPT (0.68) | MAPTKDM4EGAALMNAALDH1A1 | |
| SCHEMBL9462041 | 0.68 | KDM4E (0.44) | MAPTKDM4EGAALMNAALDH1A1 | |
| SCHEMBL23550061 | 0.67 | MAPT (0.49) | MAPTKDM4EGAALMNAALDH1A1 | |
| SCHEMBL9663925 | 0.67 | KDM4E (0.43) | MAPTKDM4EGAALMNAALDH1A1 | |
| SCHEMBL17080506 | 0.67 | FAAH (0.33) | LMNA | |
| SCHEMBL24452939 | 0.67 | MAPT (0.67) | MAPTKDM4EGAALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0118138-A1 | ((4-(4-(4-Phenyl-1-piperazinyl)phenoxymethyl)-1,3-dioxolan-2-yl)methyl)-1H-imidazoles and 1H-1,2,4-triazoles | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-09-12 | — | — | EP | disclosed |