SCHEMBL8683446

SCHEMBL8683446

CCCCCC1CCC(CCC(=O)CC2CCCCC2)CC1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.53
PKM P14618 1/20 0.41
MAPT P10636 1/20 0.41
HSD11B1 P28845 1/20 0.41
NAAA Q02083 1/20 0.41
MEN1 O00255 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
CCR2 P41597 1/20 0.40
HPGD P15428 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
KDM5A P29375 2/20 0.39
PHF8 Q9UPP1 2/20 0.39
KDM2A Q9Y2K7 2/20 0.39
KDM4C Q9H3R0 1/20 0.39
KDM4A O75164 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2990381 0.83 NAAA (0.53) CYP1A2MAPTNAAAKMT2A
SCHEMBL11625205 0.83 NAAA (0.53) CYP1A2MAPTNAAAKMT2A
SCHEMBL19508699 0.83 NAAA (0.53) CYP1A2MAPTNAAAKMT2A
SCHEMBL787945 0.83 CYP1A2 (0.48) CYP1A2MAPTNAAAMEN1KMT2A
SCHEMBL3000062 0.81 CYP1A2 (0.53) CYP1A2MAPTHSD11B1NAAAKMT2A
SCHEMBL10992587 0.81 CYP1A2 (0.59) CYP1A2MAPTNAAAKMT2AKDM5A
SCHEMBL28793847 0.81 CYP1A2 (0.59) CYP1A2MAPTNAAAKMT2AKDM5A
SCHEMBL24854724 0.81 CYP1A2 (0.52) CYP1A2MAPTHSD11B1NAAAKMT2A
Bicarbonate SCHEMBL11126117 0.81 CYP1A2 (0.63) CYP1A2PKMMAPTNAAAMEN1
SCHEMBL9571981 0.81 MAPT (0.50) CYP1A2PKMMAPTNAAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5779936-A FLUORINATED BICYCLOHEXANE OR CYCLOHEXYLETHYL CYCLOHEXANE DERIVATIVE HAVING LOW VISCOSITY AND HIGH CLEARING POINT TEMPERATURE CHISSO CORPORATION (JP) 1998-07-14 US disclosed