Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760390 | 0.95 | PDE4A (0.47) | PARP10LMNAKDM4EUSP2ALDH1A1 | |
| SCHEMBL9040138 | 0.86 | RARB (0.53) | LMNAKDM4EUSP2ALDH1A1MMP9 | |
| SCHEMBL3123864 | 0.83 | CYP4A11 (0.62) | ALDH1A1ALOX15CYP4A11CA2CYP4F2 | |
| SCHEMBL6333378 | 0.81 | HPGD (0.51) | LMNAALDH1A1CYP4A11CA2CYP4F2 | |
| SCHEMBL28065789 | 0.80 | PDE4A (0.49) | PARP10LMNAALDH1A1PDE4APDE4B | |
| SCHEMBL3540841 | 0.80 | ALDH1A1 (0.52) | LMNAKDM4EUSP2ALDH1A1MMP9 | |
| SCHEMBL8567015 | 0.80 | CA1 (0.46) | LMNAKDM4EUSP2ALDH1A1MMP9 | |
| SCHEMBL8732251 | 0.79 | CYP4A11 (0.63) | LMNAKDM4EUSP2ALDH1A1MMP9 | |
| SCHEMBL18106011 | 0.79 | CYP4A11 (0.56) | ALDH1A1ALOX15CYP4A11CA2CYP4F2 | |
| SCHEMBL6284410 | 0.78 | ALDH1A1 (0.50) | LMNAKDM4EUSP2ALDH1A1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726208-A | Heterocyclic tertiary amines | ADIR ET COMPAGNIE (FR) | 1998-03-10 | — | — | US | disclosed |