Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.42 |
| ▸ | RAB9A | P51151 | 10/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69494 | 0.77 | RAB9A (0.45) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL3683732 | 0.77 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL5965141 | 0.77 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL2821900 | 0.77 | ALDH1A1 (0.44) | NPC1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL7038858 | 0.77 | ALDH1A1 (0.44) | NPC1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL3683695 | 0.73 | NOTUM (0.42) | SMN1; SMN2HPGDMAPTALDH1A1GAA | |
| SCHEMBL70373 | 0.71 | RAB9A (0.42) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL5965271 | 0.68 | RAB9A (0.39) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL12681544 | 0.68 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL5924939 | 0.68 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662477-A1 | Heterobicyclic compounds with fungicidal activity | ISAGRO S.p.A. (IT) | 1995-07-12 | — | — | EP | claimed |
| US-5716974-A | TREATING FUNGAL PLANT DISEASES | ISAGRO S.P.A. (IT) | 1998-02-10 | — | — | US | disclosed |
| US-5594020-A | FUNGICIDE | BASF AKTIENGESELLSCHAFT (DE) | 1997-01-14 | — | — | US | disclosed |
| EP-0662477-A1 | Heterobicyclic compounds with fungicidal activity | ISAGRO S.p.A. (IT) | 1995-07-12 | — | — | EP | disclosed |